Yulianto Andreas Berny, Suwanti Lucia Tri, Widiyatno Thomas Valentinus, Suwarno Suwarno, Yunus Muchammad, Tyasningsih Wiwiek, Hidanah Sri, Sjofjan Osfar, Lokapirnasari Widya Paramita
Sains Veteriner Doctoral Program, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Faculty of Veterinary Medicine, Wijaya Kusuma Surabaya University, Surabaya, Indonesia.
Vet Med Int. 2021 Oct 8;2021:1473208. doi: 10.1155/2021/1473208. eCollection 2021.
causes coccidiosis, which has long been recognized as a disease in chickens that significantly affects the economy. The global chicken population continues to grow, and its contribution to food security increases, making it increasingly important to produce chicken meat that is safe for human and health. This study aims to prove ABY 118 to modulation of ChIFN- and ChIL-10 in chickens infected with . oocysts. This study used 100 of day-old chickens (DOC), randomly divided into 5 treatments; each treatment consists of 20 chickens. The treatments was as follows: 0 (-): negative control; 0 (+): positive control; 1: monensin; 2: probiotic 1.5 × 10 CFU/ml; and 3: probiotic 3.0 × 10 CFU/ml. At the age of 20 days, (. ) oocysts were inoculated orally at a dose of 1 × 10. The probiotic . ABY 118 was given orally through drinking water from DOC to 35 days. Monensin was given orally through feed from the age of 14-26 days. The results of statistical analysis showed that there was a significant difference ( < 0.05) between treatments on ChIFN- and ChIL-10 at 6 and 8 days postinfected with . oocysts. Based on the results of this study, it can be concluded that the use of . ABY 118 isolates at a dose of 1.5 × 10 CFU/ml and 3.0 × 10 CFU/ml per liter of drinking water can increase health by stimulation of ChIFN- and ChIL-10 in broiler infected with . oocyst.
引起球虫病，长期以来球虫病一直被认为是一种严重影响经济的鸡病。全球鸡肉产量持续增长，其对粮食安全的贡献不断增加，因此生产对人类健康安全的鸡肉变得越来越重要。本研究旨在证明ABY 118对感染 卵囊的鸡体内ChIFN-和ChIL-10的调节作用。本研究使用了100只一日龄雏鸡（DOC），随机分为5组处理；每组处理包含20只鸡。处理如下：0（-）：阴性对照；0（+）：阳性对照；1：莫能菌素；2：益生菌1.5×10⁶ CFU/ml；3：益生菌3.0×10⁶ CFU/ml。在20日龄时，以1×10⁴个的剂量口服接种 （ ）卵囊。从一日龄雏鸡到35日龄，通过饮水口服给予益生菌ABY 118。从14日龄到26日龄，通过饲料口服给予莫能菌素。统计分析结果表明，在感染 卵囊后6天和8天，各处理组之间ChIFN-和ChIL-10存在显著差异（P＜0.05）。基于本研究结果，可以得出结论，每升饮用水中使用剂量为1.5×10⁶ CFU/ml和3.0×10⁶ CFU/ml的ABY 118分离株可通过刺激感染 卵囊的肉鸡体内的ChIFN-和ChIL-10来增强健康。
