Deshmane Subhash, Kendre Prakash, Mahajan Hitendra, Jain Shirish
Department of Pharmaceutics, Rajarshi Shahu College of Pharmacy, Malvihir, India.
Department of Pharmaceutics, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, India.
Drug Dev Ind Pharm. 2021 Sep;47(9):1362-1372. doi: 10.1080/03639045.2021.1994990. Epub 2021 Oct 29.
Three-dimensional printing (3DP) technology is an innovative tool used in manufacturing medical devices, producing alloys, replacing biological tissues, producing customized dosage forms and so on. Stereolithography (SLA), a 3D printing technique, is very rapid and highly accurate and produces finished products of uniform quality. 3D formulations have been optimized with a perfect tool of artificial intelligence learning techniques. Complex designs/shapes can be fabricated through SLA using the photopolymerization principle. Different 3DP technologies are introduced and the most promising of these, SLA, and its commercial applications, are focused on. The high speed and effectiveness of SLA are highlighted. The working principle of SLA, the materials used and applications of the technique in a wide range of different sectors are highlighted in this review. An innovative idea of 3D printing customized pharmaceutical dosage forms is also presented. SLA compromises several advantages over other methods, such as cost effectiveness, controlled integrity of materials and greater speed. The development of SLA has allowed the development of printed pharmaceutical devices. Considering the present trends, it is expected that SLA will be used along with conventional methods of manufacturing of 3D model. This 3D printing technology may be utilized as a novel tool for delivering drugs on demand. This review will be useful for researchers working on 3D printing technologies.
三维打印(3DP)技术是一种用于制造医疗设备、生产合金、替代生物组织、生产定制剂型等的创新工具。立体光刻(SLA)作为一种3D打印技术,速度非常快且精度极高,能够生产出质量均匀的成品。3D配方已通过人工智能学习技术这一完美工具进行了优化。复杂的设计/形状可以利用光聚合原理通过SLA制造出来。本文介绍了不同的3DP技术,并重点关注其中最具前景的SLA及其商业应用。强调了SLA的高速性和有效性。本综述突出了SLA的工作原理、所用材料以及该技术在广泛不同领域的应用。还提出了3D打印定制药物剂型的创新理念。与其他方法相比,SLA具有若干优势,如成本效益、材料完整性可控以及速度更快。SLA的发展推动了打印制药设备的发展。考虑到当前趋势,预计SLA将与3D模型的传统制造方法一起使用。这种3D打印技术可作为一种按需给药的新型工具。本综述将对从事3D打印技术研究的人员有所帮助。