Department of Forensic Medicine, Defense Institute of Forensic Science, Criminal Investigation Command, Ministry of National Defense, Seoul, Korea.
Department of Pathology, Incheon Sejong Hospital, Incheon, Korea.
J Korean Med Sci. 2021 Oct 18;36(40):e286. doi: 10.3346/jkms.2021.36.e286.
We present autopsy findings of a 22-year-old man who developed chest pain 5 days after the first dose of the BNT162b2 mRNA vaccine and died 7 hours later. Histological examination of the heart revealed isolated atrial myocarditis, with neutrophil and histiocyte predominance. Immunohistochemical C4d staining revealed scattered single-cell necrosis of myocytes which was not accompanied by inflammatory infiltrates. Extensive contraction band necrosis was observed in the atria and ventricles. There was no evidence of microthrombosis or infection in the heart and other organs. The primary cause of death was determined to be myocarditis, causally-associated with the BNT162b2 vaccine.
我们呈现了一名 22 岁男性的尸检结果，他在接种 BNT162b2 mRNA 疫苗第一针后 5 天出现胸痛，并在 7 小时后死亡。心脏的组织学检查显示孤立性心房心肌炎，以中性粒细胞和组织细胞为主。免疫组化 C4d 染色显示心肌细胞散在的单细胞坏死，没有伴随炎症浸润。心房和心室可见广泛的收缩带坏死。心脏和其他器官均无微血栓或感染的证据。主要死亡原因为心肌炎，与 BNT162b2 疫苗有因果关系。
