SMILE 屈光手术技术后的活体共聚焦显微镜检查结果。

In vivo confocal microscopy findings after SMILE refractive surgery technique.

机构信息

Departamento de Córnea y Cirugía Refractiva, Asociación para Evitar la Ceguera en México, Hospital Luis Sánchez Bulnes, Universidad Nacional Autónoma de México, Ciudad de México, México.

Division of Comprehensive Eye Care, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, USA.

出版信息

Cir Cir. 2021;89(5):570-573. doi: 10.24875/CIRU.21000026.

DOI:10.24875/CIRU.21000026

PMID:34665161

Abstract

OBJECTIVE

To evaluate confocal microscopy finding after SMILE surgery by in vivo confocal microscopy and stromal lenticule and stromal interface accuracy planed vs measured.

METHOD

Thirty eyes of 15 patients were evaluated before and 1 month after SMILE surgery by using confocal microscopy. Cellular morphology was studied. Planed stromal lenticule thickness was compared vs measured stromal lenticule thickness after surgery by comparing the total stromal corneal thickness before vs after surgery. Stromal corneal interface was evaluated and depth of this planed interface was compared vs measured post-surgery interface depth.

RESULTS

Sub-epithelial nerve plexus was absent at 1 month after surgery. Activated keratocytes were found before and after stromal corneal interface depth. There was not statistical significant difference between mean planed stromal lenticule vs. post-surgery measured (102.3 ± 25.7 vs. 104.2 ± 29.9 mm; p = 0.73). There was not statistical significant difference between mean planed stromal interface depth vs. post-surgical measured (113.7 ± 8.2 vs. 120.5 ± 17.3 mm; p = 0.058).

CONCLUSIONS

Confocal microscopy is useful to evaluate changes after SMILE surgery; lenticule thickness and stromal interface depth are exact.

摘要

目的

通过活体共聚焦显微镜评估 SMILE 手术后的共焦显微镜检查结果，并对计划的基质透镜厚度与测量的基质透镜厚度以及计划的基质界面深度与测量的基质界面深度进行比较。

方法

对 15 例 30 只眼 SMILE 手术前后进行共焦显微镜检查，研究细胞形态。通过比较手术前后总基质角膜厚度，比较计划的基质透镜厚度与术后测量的基质透镜厚度。评估基质角膜界面，并比较该计划界面深度与术后测量的界面深度。

结果

术后 1 个月，上皮下神经丛缺失。在基质角膜界面深度前后均发现活化的角膜细胞。平均计划的基质透镜厚度与术后测量的（102.3 ± 25.7 vs. 104.2 ± 29.9 mm；p = 0.73）之间无统计学显著差异。平均计划的基质界面深度与术后测量的（113.7 ± 8.2 vs. 120.5 ± 17.3 mm；p = 0.058）之间无统计学显著差异。