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[共焦线阵光学相干断层扫描]

[Confocal line-field OCT].

作者信息

Schuh Sandra, Ruini C, Sattler E, Welzel J

机构信息

Klinik für Dermatologie und Allergologie, Universitätsklinikum Augsburg, Sauerbruchstr. 6, 86179, Augsburg, Deutschland.

Klinik und Poliklinik für Dermatologie und Allergologie, Klinikum der Universität München, LMU München, München, Deutschland.

出版信息

Hautarzt. 2021 Dec;72(12):1039-1047. doi: 10.1007/s00105-021-04900-7. Epub 2021 Oct 20.

DOI:10.1007/s00105-021-04900-7
PMID:34668985
Abstract

Optical coherence tomography (OCT) and confocal laser microscopy (CLSM) are established non-invasive methods in clinical dermatological routine diagnosis. Whereas CLSM is especially useful to distinguish between nevi and melanoma, OCT is suitable for the diagnosis and differentiation of non-melanoma skin cancer. Line-field confocal optical coherence tomography (LC-OCT) is a new innovative device, which has better cellular resolution than OCT and a higher penetration depth than CLSM. Similar to CLSM, LC-OCT also allows 3D images in real time to be taken. Therefore LC-OCT is very useful for the examination of skin lesions of all kinds, since it unites the features of CLSM and OCT.

摘要

光学相干断层扫描(OCT)和共聚焦激光显微镜(CLSM)是临床皮肤科常规诊断中已确立的非侵入性方法。虽然CLSM对区分痣和黑色素瘤特别有用,但OCT适用于非黑色素瘤皮肤癌的诊断和鉴别。线场共聚焦光学相干断层扫描(LC-OCT)是一种新型创新设备,其细胞分辨率比OCT更好,穿透深度比CLSM更高。与CLSM类似,LC-OCT也允许实时拍摄三维图像。因此,LC-OCT对于各种皮肤病变的检查非常有用,因为它结合了CLSM和OCT的特点。

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本文引用的文献

1
Line-field confocal optical coherence tomography of pyogenic granulomas in children: report of two cases.儿童化脓性肉芽肿的线场共焦光学相干断层扫描:2例报告
J Eur Acad Dermatol Venereol. 2022 Jan;36(1):e37-e39. doi: 10.1111/jdv.17608. Epub 2021 Sep 1.
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Line-field confocal optical coherence tomography for the in vivo real-time diagnosis of different stages of keratinocyte skin cancer: a preliminary study.线阵共聚焦光学相干断层扫描用于角质形成细胞皮肤癌不同阶段的实时体内诊断:初步研究。
J Eur Acad Dermatol Venereol. 2021 Dec;35(12):2388-2397. doi: 10.1111/jdv.17603. Epub 2021 Sep 24.
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Line-field confocal optical coherence tomography for non-invasive diagnosis of lichenoid dermatoses of the childhood: A case series.
揭示炎症性皮肤病的特征性模式:应用光学相干断层扫描和线扫描共聚焦光学相干断层扫描的综合双成像方法。
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Diagnostic Accuracy of Line-Field Confocal Optical Coherence Tomography for the Diagnosis of Skin Carcinomas.线场共聚焦光学相干断层扫描技术对皮肤癌诊断的诊断准确性
Diagnostics (Basel). 2023 Jan 18;13(3):361. doi: 10.3390/diagnostics13030361.
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Line-Field Confocal Optical Coherence Tomography: A New Tool for the Differentiation between Nevi and Melanomas?线场共焦光学相干断层扫描:一种区分痣和黑色素瘤的新工具?
Cancers (Basel). 2022 Feb 23;14(5):1140. doi: 10.3390/cancers14051140.
线场共聚焦光学相干断层扫描用于儿童苔藓样皮肤病的无创诊断:病例系列
Skin Res Technol. 2021 Nov;27(6):1178-1181. doi: 10.1111/srt.13075. Epub 2021 Jul 6.
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Line-field confocal optical coherence tomography for actinic keratosis and squamous cell carcinoma: a descriptive study.线阵共焦光学相干断层扫描在光化性角化病和鳞状细胞癌中的应用:一项描述性研究。
Clin Exp Dermatol. 2021 Dec;46(8):1530-1541. doi: 10.1111/ced.14801. Epub 2021 Sep 24.
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Line-field optical coherence tomography: in vivo diagnosis of basal cell carcinoma subtypes compared with histopathology.线阵光学相干断层扫描:与组织病理学相比,对基底细胞癌亚型的体内诊断。
Clin Exp Dermatol. 2021 Dec;46(8):1471-1481. doi: 10.1111/ced.14762. Epub 2021 Sep 24.
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Line-field confocal optical coherence tomography: a novel, non-invasive imaging technique for a rapid, in-vivo diagnosis of herpes infection of the skin.线场共焦光学相干断层扫描:一种用于快速、体内诊断皮肤疱疹感染的新型非侵入性成像技术。
J Eur Acad Dermatol Venereol. 2021 Jun;35(6):e404-e406. doi: 10.1111/jdv.17182. Epub 2021 Mar 5.
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Comparison of line-field confocal optical coherence tomography images with histological sections: Validation of a new method for in vivo and non-invasive quantification of superficial dermis thickness.线阵共焦光学相干断层扫描图像与组织切片的比较:一种新的用于活体和非侵入性定量浅层真皮厚度的方法的验证。
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Optical coherence tomography for diagnosing skin cancer in adults.光学相干断层扫描技术在成人皮肤癌诊断中的应用
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Reflectance confocal microscopy for diagnosing keratinocyte skin cancers in adults.成人角质形成细胞皮肤癌诊断中的反射式共聚焦显微镜检查
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