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基于药学的干预措施在美国提高 HIV 暴露前预防用药的使用率:范围综述。

Pharmacy-Based Interventions to Increase Use of HIV Pre-exposure Prophylaxis in the United States: A Scoping Review.

机构信息

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, 60 College Street, New Haven, CT, 06510, USA.

Johns Hopkins School of Nursing, 525 N. Wolfe Street, Baltimore, MD, 21205, USA.

出版信息

AIDS Behav. 2022 May;26(5):1377-1392. doi: 10.1007/s10461-021-03494-4. Epub 2021 Oct 20.

Abstract

HIV pre-exposure prophylaxis (PrEP) remains underutilized in the U.S. Since greater than 85% of PrEP prescriptions are filled at commercial pharmacies, pharmacists are uniquely positioned to increase PrEP use. This scoping review explores pharmacy-based initiatives to increase PrEP use. We searched PubMed, PsycINFO, CINAHL, and Scopus for peer-reviewed studies on pharmacist-led interventions to increase PrEP use or pharmacy-based PrEP initiatives. Forty-nine articles were included in this review. Overall, studies demonstrated that patients expressed strong support for pharmacist prescription of PrEP. Three intervention designs compared changes in PrEP initiation or knowledge pre- and post-intervention. Commentary/review studies recommended PrEP training for pharmacists, policy changes to support pharmacist screening for HIV and PrEP prescription, and telemedicine to increase prescriptions. Pharmacists could play key roles in improving PrEP use in the U.S. Studies that assess improvements in PrEP use after interventions such as PrEP prescription, PrEP-specific training, and adherence monitoring by pharmacists are needed.

摘要

HIV 暴露前预防 (PrEP) 在 美国的应用仍不充分。由于超过 85%的 PrEP 处方是在商业药店开具的,药剂师在增加 PrEP 的使用方面具有独特的优势。本范围综述探讨了基于药房的举措,以增加 PrEP 的使用。我们在 PubMed、PsycINFO、CINAHL 和 Scopus 中搜索了关于药剂师主导的干预措施以增加 PrEP 使用或基于药房的 PrEP 计划的同行评议研究。本综述纳入了 49 篇文章。总体而言,研究表明患者强烈支持药剂师开具 PrEP 处方。三种干预设计比较了干预前后 PrEP 起始或知识的变化。评论/综述研究建议对药剂师进行 PrEP 培训、政策改革以支持药剂师对 HIV 和 PrEP 处方的筛查,以及远程医疗以增加处方。药剂师可以在美国改善 PrEP 使用方面发挥关键作用。需要评估干预措施(如 PrEP 处方、PrEP 特定培训和药剂师的依从性监测)后 PrEP 使用的改善情况的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8feb/8527816/ada51d22e8fc/10461_2021_3494_Fig1_HTML.jpg

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