Bolshunov A V, Poleva R P, Ragozina E A, Khderi Kh
Research Institute of Eye Diseases, Moscow, Russia.
Vestn Oftalmol. 2021;137(5. Vyp. 2):346-353. doi: 10.17116/oftalma2021137052346.
Pigment dispersion syndrome (PDS) is a condition that mostly affects young men with myopic refraction. PDS is characterized by the presence of Krukenberg spindle, peripheral iris defects, significant trabecular meshwork pigmentation, as well as convex iris configuration. Such configuration can cause friction of iris's posterior pigment layer on its ligaments, which leads to the release of pigment and its accumulation mostly in the structures of the anterior chamber. Over time PDS can progress into pigmentary glaucoma (PG), which in turn can lead to permanent loss of vision. This review analyzes available data on diagnosis and treatment of PDS and PG.
色素播散综合征（PDS）是一种主要影响患有近视屈光不正的年轻男性的病症。PDS的特征是存在克氏梭、周边虹膜缺损、显著的小梁网色素沉着以及虹膜凸面形态。这种形态会导致虹膜后色素层与其韧带之间产生摩擦，从而导致色素释放，且色素大多在前房结构中积聚。随着时间推移，PDS可进展为色素性青光眼（PG），进而可导致永久性视力丧失。本综述分析了关于PDS和PG诊断与治疗的现有数据。
