一种评估血液系统疾病中无效红细胞生成的新指标为镰状细胞病提供了新见解。 - Suppr

A novel index to evaluate ineffective erythropoiesis in hematological diseases offers insights into sickle cell disease.

作者信息

Brewin John, El Hoss Sara, Strouboulis John, Rees David

机构信息

Molecular Haematology, Comprehensive Cancer Centre, School of Cancer and Pharmaceutical Sciences, King's College London, United Kingdom; Department of Haematological Medicine, King's College Hospital, London, United Kingdom.

Molecular Haematology, Comprehensive Cancer Centre, School of Cancer and Pharmaceutical Sciences, King's College London, United Kingdom.

出版信息

Haematologica. 2022 Jan 1;107(1):338-341. doi: 10.3324/haematol.2021.279623.

DOI:10.3324/haematol.2021.279623

PMID:34670360

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8719095/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7b7/8719095/1e6e26f4bc1c/107338.fig1.jpg

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Genome wide association study of silent cerebral infarction in sickle cell disease (HbSS and HbSC).全基因组关联研究镰状细胞病（HbSS 和 HbSC）中的无症状性脑梗死。

Haematologica. 2021 Jun 1;106(6):1770-1773. doi: 10.3324/haematol.2020.265827.

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Haematologica. 2021 Oct 1;106(10):2707-2719. doi: 10.3324/haematol.2020.265462.

Pathologic angiogenesis in the bone marrow of humanized sickle cell mice is reversed by blood transfusion.人源化镰状细胞小鼠骨髓中的病理性血管生成可通过输血逆转。

Blood. 2020 Jun 4;135(23):2071-2084. doi: 10.1182/blood.2019002227.

The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease.镰状细胞病治疗中不断演变的药物治疗格局。

Mediterr J Hematol Infect Dis. 2020 Jan 1;12(1):e2020010. doi: 10.4084/MJHID.2020.010. eCollection 2020.

Hydroxyurea use in young infants with sickle cell disease.羟基脲在镰状细胞病婴幼儿中的应用。

Pediatr Blood Cancer. 2019 Jul;66(7):e27650. doi: 10.1002/pbc.27650. Epub 2019 Feb 7.

A systematic review of known mechanisms of hydroxyurea-induced fetal hemoglobin for treatment of sickle cell disease.对羟基脲诱导胎儿血红蛋白治疗镰状细胞病已知机制的系统评价。

Expert Rev Hematol. 2015 Oct;8(5):669-79. doi: 10.1586/17474086.2015.1078235. Epub 2015 Sep 1.

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Am J Hematol. 2011 Feb;86(2):123-54. doi: 10.1002/ajh.21952.

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A novel index to evaluate ineffective erythropoiesis in hematological diseases offers insights into sickle cell disease.

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