Center for Improving Patient and Population Health and Rogel Cancer Center, University of Michigan, North Campus Research Complex, Bldg 16, Room 409E, 2800 Plymouth Road, Ann Arbor, MI, 48109, USA.
Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI, USA.
BMC Geriatr. 2021 Oct 20;21(1):580. doi: 10.1186/s12877-021-02545-8.
Despite a growing burden of Alzheimer's Disease and related dementias (ADRD) in the US, the relationship between health care and cognitive impairment prevention is unclear. Primary care manages risk causing conditions and risk reducing behaviors for dementia, so we examine the association between individual and area-level access to primary care and cognitive impairment in the REasons for Geographic And Racial Differences in Stroke (REGARDS) study.
REGARDS participants with a cognitive assessment and vascular measurements at their baseline visit were included in this cross-sectional analysis. Cognitive impairment was defined as a Six-Item Screener (SIS) score < 5. Primary care supply, primary care utilization and emergency department (ED) utilization were measured at the primary care service area (PCSA) level based on participant's address. Individual access to care was self-reported. Models were adjusted for confounding by demographics, socioeconomic status and behavioral risk factors.
Among 25,563 adults, living in a PCSA with low primary care supply was associated with 25% higher odds of cognitive impairment (OR 1.25 CI 1.07-1.45). Not having a regular source of medical care was associated with 14% higher odds of cognitive impairment (OR 1.14 CI 1.02-1.28), and living in a PCSA with high emergency department utilization was associated with 12% higher odds of cognitive impairment (OR 1.12 CI 1.02-1.23).
Our results are an important first step in understanding how health care may prevent cognitive impairment. They highlight the importance of primary care and suggest future work clarifying its role in preventing cognitive decline is imperative.
尽管美国阿尔茨海默病和相关痴呆症(ADRD)的负担不断增加,但医疗保健与认知障碍预防之间的关系尚不清楚。初级保健管理导致痴呆症的风险因素和降低风险的行为,因此我们在 REasons for Geographic And Racial Differences in Stroke(REGARDS)研究中检查了个体和地区层面获得初级保健与认知障碍之间的关系。
本横断面分析纳入了在基线访视时进行认知评估和血管测量的 REGARDS 参与者。认知障碍定义为六项目筛查(SIS)评分<5。根据参与者的地址,在初级保健服务区(PCSA)水平上测量初级保健供应、初级保健利用和急诊部(ED)利用。个体获得护理的情况是自我报告的。模型通过人口统计学、社会经济状况和行为风险因素进行了混杂因素调整。
在 25563 名成年人中,居住在初级保健供应不足的 PCSA 中与认知障碍的几率增加 25%相关(OR 1.25,CI 1.07-1.45)。没有固定的医疗来源与认知障碍的几率增加 14%相关(OR 1.14,CI 1.02-1.28),而居住在 ED 利用率较高的 PCSA 与认知障碍的几率增加 12%相关(OR 1.12,CI 1.02-1.23)。
我们的结果是了解医疗保健如何预防认知障碍的重要的第一步。它们突出了初级保健的重要性,并表明未来的工作需要阐明其在预防认知能力下降方面的作用。