Department of Gynecology and Obstetrics, Santo Spirito Hospital, Pescara, Italy.
Department of Gynecology and Obstetrics, University Hospital Maggiore della Carita, Novara, Italy.
JSLS. 2021 Jul-Sep;25(3). doi: 10.4293/JSLS.2021.00044.
Near-infrared fluorescence (NIRF) of the Firefly® system has become a useful and widespread technique for the visualization and detection of tumors, sentinel lymphnodes, and vascular/anatomical structures.
Between February 1, 2017 to September 30, 2019, a total of 25 patients affected by benign and malignant pathologies underwent robotic surgery by the use of organ transillumination with the concomitant Firefly®. We analyzed the pre-operative patients' characteristics (age and body mass index [BMI], previous abdominal surgeries and systemic disease); pre-operative diagnosis, surgical procedure and approach (multiport or single site), transilluminated organ, surgical outcomes (operating time, incidence of intraoperative complications, and incidence of conversion to other surgery); and postoperative outcome. The surgical procedures included: four bladder endometriosis nodules resections, one pelvic lymphadenectomy with ureterolysis, and 23 hysterectomies.
The average operating time was 283.3 (+/- 76.9) minutes, there were no intra-operative complications or laparotomic conversions. The average recovery days were 5.9. There have been three grade 2 post-surgical complications, following the Memorial Sloan Kettering Cancer Center Surgical Secondary Events System classification. The combination of NIRF and transillumination allows a clear view of the anatomical landmarks and the resection margins.
It's likely that improvement in the anatomical detail could confer a greater surgical safety with lower percentage of intra and post-surgical complications and sparing of safe tissue. To evaluate the validity of these techniques in a larger number of patients and compare these new surgical procedures with standard ones, further studies are needed.
萤火虫®系统的近红外荧光(NIRF)已成为可视化和检测肿瘤、前哨淋巴结以及血管/解剖结构的有用且广泛应用的技术。
2017 年 2 月 1 日至 2019 年 9 月 30 日期间,共有 25 名患有良性和恶性疾病的患者接受了机器人手术,同时使用器官透照术和萤火虫®进行辅助。我们分析了术前患者的特征(年龄和体重指数 [BMI]、既往腹部手术和全身疾病);术前诊断、手术程序和途径(多孔或单部位)、透照器官、手术结果(手术时间、术中并发症发生率和转为其他手术的发生率);以及术后结果。手术程序包括:4 例膀胱子宫内膜异位症结节切除术、1 例盆腔淋巴结切除术伴输尿管松解术和 23 例子宫切除术。
平均手术时间为 283.3(+/-76.9)分钟,无术中并发症或剖腹转换。平均恢复天数为 5.9 天。根据纪念斯隆凯特琳癌症中心外科二次事件系统分类,有 3 例 2 级术后并发症。NIRF 和透照术的结合可以清晰地显示解剖标志和切除边缘。
改善解剖细节可能会提高手术安全性,降低术中及术后并发症的发生率,并保护安全组织。为了在更多患者中评估这些技术的有效性,并将这些新的手术程序与标准程序进行比较,需要进一步的研究。