Dick White Referrals, Six Mile Bottom, Cambridgeshire, CB8 0UH, UK.
AniCura AOI Center AG, Hünenberg, 6331, Switzerland.
J Small Anim Pract. 2022 Jul;63(7):497-511. doi: 10.1111/jsap.13444. Epub 2021 Oct 20.
Cutaneous and subcutaneous mast cell tumours are common neoplasms in the dog. While the majority can be treated with adequate local therapy alone, a subset demonstrates a biologically aggressive behaviour associated with local recurrence or metastasis. This article reviews the diagnosis and tumour staging of canine mast cell tumours alongside treatment options and the evidence supporting their use. In addition, prognostic markers are evaluated to highlight how one can recognise mast cell tumours that may behave in a biologically aggressive manner as well as the challenges of tumours that are large, infiltrative or in locations not amenable to wide surgical excision.
皮肤和皮下组织 mast 细胞肿瘤是犬的常见肿瘤。虽然大多数肿瘤仅通过充分的局部治疗即可治愈,但有一部分表现出与局部复发或转移相关的生物学侵袭性行为。本文综述了犬 mast 细胞肿瘤的诊断和肿瘤分期,以及治疗选择和支持其使用的证据。此外,还评估了预后标志物,以突出哪些 mast 细胞肿瘤可能具有生物学侵袭性行为,以及哪些肿瘤较大、浸润性或位于难以广泛切除的位置所带来的挑战。