• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

约瑟夫病和橄榄脑桥小脑萎缩中的谷氨酸和苹果酸脱氢酶活性

Glutamate and malate dehydrogenase activities in Joseph disease and olivopontocerebellar atrophy.

作者信息

Grossman A, Rosenberg R N, Warmoth L

出版信息

Neurology. 1987 Jan;37(1):106-11. doi: 10.1212/wnl.37.1.106.

DOI:10.1212/wnl.37.1.106
PMID:3467219
Abstract

The activities of brain glutamate dehydrogenase and malate dehydrogenase were not statistically different in samples from patients with autosomal dominant olivopontocerebellar atrophy or Joseph disease compared with control subject samples. These two enzymes are thus not involved in the pathogenesis of these two separate dominantly inherited diseases.

摘要

与对照样本相比,常染色体显性遗传性橄榄体脑桥小脑萎缩症(OPCA)患者或约瑟夫病患者样本中的脑谷氨酸脱氢酶和苹果酸脱氢酶活性无统计学差异。因此,这两种酶不参与这两种独立的显性遗传性疾病的发病机制。

相似文献

1
Glutamate and malate dehydrogenase activities in Joseph disease and olivopontocerebellar atrophy.约瑟夫病和橄榄脑桥小脑萎缩中的谷氨酸和苹果酸脱氢酶活性
Neurology. 1987 Jan;37(1):106-11. doi: 10.1212/wnl.37.1.106.
2
Glutamate dehydrogenase in OPCA.橄榄体脑桥小脑萎缩中的谷氨酸脱氢酶
Neurology. 1987 Oct;37(10):1687. doi: 10.1212/wnl.37.10.1687-b.
3
Degenerative neurological disorders associated with deficiency of glutamate dehydrogenase.与谷氨酸脱氢酶缺乏相关的退行性神经疾病
J Neurol. 1989 Feb;236(2):111-4. doi: 10.1007/BF00314407.
4
Low leukocyte glutamate dehydrogenase activity does not correlate with a particular type of multiple system atrophy.低白细胞谷氨酸脱氢酶活性与特定类型的多系统萎缩无关。
J Neurol Neurosurg Psychiatry. 1988 Dec;51(12):1508-11. doi: 10.1136/jnnp.51.12.1508.
5
Brain choline acetyltransferase reduction in dominantly inherited olivopontocerebellar atrophy.
Ann Neurol. 1987 Aug;22(2):272-5. doi: 10.1002/ana.410220214.
6
Decreased glutamate dehydrogenase protein in spinocerebellar degeneration.脊髓小脑变性中谷氨酸脱氢酶蛋白减少。
J Neurol Neurosurg Psychiatry. 1988 Aug;51(8):1078-80. doi: 10.1136/jnnp.51.8.1078.
7
Normal cerebellar glutamate dehydrogenase protein in spinocerebellar degeneration.脊髓小脑变性中正常的小脑谷氨酸脱氢酶蛋白
J Neurol Neurosurg Psychiatry. 1989 May;52(5):666-8. doi: 10.1136/jnnp.52.5.666.
8
Cerebellar glutamate metabolizing enzymes in spinocerebellar ataxia type I.
Metab Brain Dis. 1994 Mar;9(1):97-103. doi: 10.1007/BF01996077.
9
Non-Alzheimer-type pattern of brain cholineacetyltransferase reduction in dominantly inherited olivopontocerebellar atrophy.
Ann Neurol. 1989 Sep;26(3):362-7. doi: 10.1002/ana.410260309.
10
Glutamate dehydrogenase deficiency in Machado-Joseph disease.马查多-约瑟夫病中的谷氨酸脱氢酶缺乏症。
Can J Neurol Sci. 1993 May;20(2):147-50. doi: 10.1017/s0317167100047727.

引用本文的文献

1
Sulfamethoxazole-trimethoprim double-blind, placebo-controlled, crossover trial in Machado-Joseph disease: sulfamethoxazole-trimethoprim increases cerebrospinal fluid level of biopterin.磺胺甲恶唑-甲氧苄啶治疗马查多-约瑟夫病的双盲、安慰剂对照、交叉试验:磺胺甲恶唑-甲氧苄啶可提高脑脊液中生物蝶呤水平。
J Neural Transm Gen Sect. 1995;102(2):159-72. doi: 10.1007/BF01276511.
2
Cerebellar glutamate metabolizing enzymes in spinocerebellar ataxia type I.
Metab Brain Dis. 1994 Mar;9(1):97-103. doi: 10.1007/BF01996077.
3
Normal cerebellar glutamate dehydrogenase protein in spinocerebellar degeneration.脊髓小脑变性中正常的小脑谷氨酸脱氢酶蛋白
J Neurol Neurosurg Psychiatry. 1989 May;52(5):666-8. doi: 10.1136/jnnp.52.5.666.
4
Multiple system degeneration with glutamate dehydrogenase deficiency: pathology and biochemistry.伴有谷氨酸脱氢酶缺乏的多系统变性:病理学与生物化学
J Neurol Neurosurg Psychiatry. 1990 Dec;53(12):1099-101. doi: 10.1136/jnnp.53.12.1099.