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高压策略:震碎食管——诊断容易治疗难。

High-Pressure Tactics: Jackhammer Esophagus-Diagnosing Is Easier than Treating.

机构信息

Division of General and Foregut Surgery, Department of Biomedical Sciences for Health, IRCCS Policlinico San Donato, University of Milan, Milan, Italy.

Department of General and Foregut Surgery, I.R.C.C.S. Policlinico San Donato, University of Milan, Piazza Malan 1, San Donato Milanese, 20097, Milan, Italy.

出版信息

Dig Dis Sci. 2022 Apr;67(4):1200-1203. doi: 10.1007/s10620-021-07279-6. Epub 2021 Oct 21.

DOI:10.1007/s10620-021-07279-6
PMID:34674073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8529866/
Abstract

Diagnosis of esophageal disorders is well ahead of available treatment options. With HRM, for example, one can identify numerous conditions and their variants, which may lose meaning if the clinical and therapeutic implications of these subclassifications are limited. We report an exemplary case of a patient with hiatal hernia complaining of reflux, dysphagia, and chest pain refractory to medical treatment. Jackhammer esophagus was diagnosed and a hybrid approach consisting of POEM and concomitant crural repair and Dor fundoplication is proposed.

摘要

食管疾病的诊断远远领先于现有治疗选择。例如,通过高分辨率测压(HRM),可以识别出许多病症及其亚型,但如果这些亚型的临床和治疗意义有限,它们可能就失去了意义。我们报告了一例食管裂孔疝患者的典型病例,该患者抱怨反流、吞咽困难和胸痛,且对药物治疗无反应。诊断为“贲门失弛缓症”,提出了一种混合治疗方法,包括经口内镜下肌切开术(POEM)以及同时进行的膈脚修复和 Dor 胃底折叠术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e13/8529866/283335e5faff/10620_2021_7279_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e13/8529866/a3338e0cde9c/10620_2021_7279_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e13/8529866/7f5ef6ddd9d9/10620_2021_7279_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e13/8529866/283335e5faff/10620_2021_7279_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e13/8529866/a3338e0cde9c/10620_2021_7279_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e13/8529866/7f5ef6ddd9d9/10620_2021_7279_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e13/8529866/283335e5faff/10620_2021_7279_Fig3_HTML.jpg

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本文引用的文献

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Esophageal motility disorders on high-resolution manometry: Chicago classification version 4.0.高分辨率食管动力障碍:芝加哥分类版本 4.0。
Neurogastroenterol Motil. 2021 Jan;33(1):e14058. doi: 10.1111/nmo.14058.
2
Endoscopic management of gastrointestinal motility disorders - part 1: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.胃肠动力障碍的内镜处理 - 第 1 部分:欧洲胃肠道内镜学会 (ESGE) 指南。
Endoscopy. 2020 Jun;52(6):498-515. doi: 10.1055/a-1160-5549. Epub 2020 May 6.
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Long-term outcomes of per-oral endoscopic myotomy compared to laparoscopic Heller myotomy for achalasia: a single-center experience.
经口内镜肌切开术与腹腔镜 Heller 肌切开术治疗贲门失弛缓症的长期疗效比较:单中心经验。
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Prospective serial diagnostic study: the effects of position and provocative tests on the diagnosis of oesophageal motility disorders by high-resolution manometry.前瞻性系列诊断研究:体位和激发试验对高分辨率测压法诊断食管动力障碍的影响。
Aliment Pharmacol Ther. 2020 Apr;51(7):706-718. doi: 10.1111/apt.15658. Epub 2020 Feb 13.
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Changes in high-resolution manometric diagnosis over time: implications for clinical decision-making.高分辨率测压诊断随时间的变化:对临床决策的影响。
Dis Esophagus. 2020 Mar 16;33(3). doi: 10.1093/dote/doz094.
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Clinical efficacy of per-oral endoscopic myotomy (POEM) for spastic esophageal disorders: a systematic review and meta-analysis.经口内镜下肌切开术(POEM)治疗痉挛性食管障碍的临床疗效:系统评价和荟萃分析。
Surg Endosc. 2020 Feb;34(2):707-718. doi: 10.1007/s00464-019-06819-6. Epub 2019 May 9.
7
Jackhammer esophagus: Assessing the balance between prepeak and postpeak contractile integral.震波食道:评估收缩积分前峰和后峰之间的平衡。
Neurogastroenterol Motil. 2018 May;30(5):e13262. doi: 10.1111/nmo.13262. Epub 2017 Nov 29.
8
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Gastrointest Endosc. 2018 Apr;87(4):934-943.e18. doi: 10.1016/j.gie.2017.10.022. Epub 2017 Nov 2.
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Peroral endoscopic myotomy for Jackhammer esophagus: to cut or not to cut the lower esophageal sphincter.经口内镜下肌切开术治疗风钻样食管:是否切开食管下括约肌
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Importance of Esophageal Manometry and pH Monitoring in the Evaluation of Patients with Refractory Gastroesophageal Reflux Disease: A Multicenter Study.食管测压和pH监测在难治性胃食管反流病患者评估中的重要性:一项多中心研究
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