Selvaraj Jayaraman, Vishnupriya Veeraraghavan, Sardar Hussain, Balakrishna Janardhana Papayya, Rex Josephine, Mohan Surapaneni Krishna, Vijayalakshmi Periyasamy, Ponnulakshmi Rajagopal
Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, India.
Department of Biotechnology, Government Science College, Chitradurga-577501, Karnataka, India.
Bioinformation. 2020 Oct 31;16(10):753-758. doi: 10.6026/97320630016753. eCollection 2020.
Cyclooxygenase-2 (COX-2) is liked with breast cancer. Therefore, it is of interest to design and develop new yet effective compounds against COX-2 from medicinal plants such as the natural alkaloid compounds. We document the optimal binding features of aristolochicacid with COX-2 protein for further consideration.
环氧化酶-2（COX-2）与乳腺癌有关。因此，从药用植物（如天然生物碱化合物）中设计和开发针对COX-2的新型有效化合物具有重要意义。我们记录了马兜铃酸与COX-2蛋白的最佳结合特征以供进一步研究。
