Experimental models of head injury.

Experimental research in studies of head injury may be directed along theoretical, mechanical and experimental animal and clinical lines. The parameter of the results compared may thus be the mechanics of skull or the skull contents, pathophysiological changes or pathomorphological lesions. Due to the variation of the daily accidents and resulting injuries each series of problems must be studied with suitable technique. Often the various types of studies determine the possibility of interpreting the results for clinical analysis and prevention. However, this is often possible if all experimental conditions and parameters studied are precisely defined. Movements, deformations of skull and the intracranial contents, results from rotational and angular acceleration and velocities as well as the direction and the site of impact in the human being must always be considered.