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一名中国男性的褶叠性汗孔角化症病例报告。

A Case Report of Porokeratosis Ptychotropica in a Chinese Man.

作者信息

Ou Xinjia, Wang Ping, Chen Wentao, Wu Weiwei, Lu Jiejie

机构信息

Department of Dermatology, Hainan Wanning People's Hospital, Wanning, Hainan, People's Republic of China.

Department of Dermatology, The Fifth People's Hospital of Hainan Province, Branch of National Clinical Research Center for Skin and Immune Disease, Haikou, Hainan, People's Republic of China.

出版信息

Clin Cosmet Investig Dermatol. 2021 Oct 7;14:1449-1451. doi: 10.2147/CCID.S334682. eCollection 2021.

Abstract

Porokeratosis ptychotropica is a rare form of porokeratosis characterized by dyskeratotic skin lesions around genital area or gluteal cleft. Herein, a case of porokeratosis ptychotropica was reported. The patient was a 35-year-old man, who complained of pruritic papules and plaques in the perianal and buttock region for thirteen years. On examination, well-demarcated brown plaques with a verrucous white surface and multiple satellite papules were located along the gluteal folds and buttocks sparing the anus. Histopathological examination was consistent with porokeratosis. Combined with clinical manifestations and histopathologic changes, the patient was diagnosed as porokeratosis ptychotropica. He was treated with oral acitretin 30mg/d and CO laser treatment, but the lesions showed no evident improvement after three months. Although it is not a new case, this condition is an extremely rare one that must be reviewed and emphasized. The dermatologist should keep porokeratosis ptychotropica in mind as one differential diagnosis for pruritic papules in the anogenital region.

摘要

向心性匐行性角化病是一种罕见的角化病,其特征为生殖器区域或臀裂周围出现角化不良性皮肤损害。在此,报告一例向心性匐行性角化病病例。患者为一名35岁男性,主诉肛周和臀部瘙痒性丘疹及斑块13年。检查发现,沿臀褶和臀部有边界清晰的褐色斑块,表面呈疣状白色,并有多个卫星状丘疹,肛门未受累。组织病理学检查结果与角化病相符。结合临床表现和组织病理学变化,该患者被诊断为向心性匐行性角化病。给予患者口服阿维A 30mg/d及CO2激光治疗,但3个月后皮损无明显改善。尽管这不是一个新病例,但这种情况极为罕见,必须予以回顾和强调。皮肤科医生应将向心性匐行性角化病作为肛门生殖器区域瘙痒性丘疹的鉴别诊断之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3ac/8504708/906441ab422e/CCID-14-1449-g0001.jpg

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