Baden T J, Gammon W R
Arch Dermatol. 1987 Jan;123(1):88-90.
We describe a patient with myelomonocytic leukemia who demonstrated striking leukemic infiltration in the scar of a recent Hickman catheter placement. This cutaneous involvement occurred initially without signs of systemic relapse. A comparative review of leukemic cell physiology provides several possible reasons for this extramedullary infiltration, including the greater functional maturity, deformability, adhesiveness, and ability to cluster of myelomonocytic and monocytic leukemia cells relative to other leukemias. A careful cutaneous examination, with particular attention to recent scars, may provide the only evidence of relapse in adult leukemia.
我们描述了一名骨髓单核细胞白血病患者，其在近期放置的希克曼导管的瘢痕处出现了显著的白血病浸润。这种皮肤受累最初并无全身复发的迹象。对白血病细胞生理学的比较性综述为这种髓外浸润提供了几个可能的原因，包括相对于其他白血病，骨髓单核细胞和单核细胞白血病细胞具有更高的功能成熟度、可变形性、粘附性以及聚集能力。仔细的皮肤检查，尤其关注近期的瘢痕，可能是成人白血病复发的唯一证据。
