Caumette Elsa, Vaz-Luis Inès, Pinto Sandrine, Havas Julie, Bovagnet Thomas, Ruiz de Azua Garazi, Di Meglio Antonio, Martin Anne-Laure, Everhard Sibille, Cottu Paul, Vanlemmens Laurence, Jouannaud Christelle, Lerebours Florence, Dumas Agnès, Menvielle Gwenn
IPLESP, Équipe de Recherche en Épidémiologie Sociale, INSERM, Institut Pierre Louis d'Épidémiologie et de Santé Publique, Sorbonne Université, 75012 Paris, France.
Department of maieutics, University of Montpellier, 34000 Montpellier, France.
Curr Oncol. 2021 Oct 1;28(5):3866-3875. doi: 10.3390/curroncol28050330.
Return to work (RTW) after breast cancer is associated with improved quality of life. The link between household characteristics and RTW remains largely unknown. The aim of this study was to examine the effect of the family situation on women's RTW two years after breast cancer. We used data of a French prospective cohort of women diagnosed with stage I-III, primary breast cancer (CANTO, NCT01993498). Among women employed at diagnosis and under 57 years old, we assessed the association between household characteristics (living with a partner, marital status, number and age of economically dependent children, support by the partner) and RTW. Logistic regression models were adjusted for age, household income, stage, comorbidities, treatments and their side effects. Analyzes stratified by age and household income were performed to assess the association between household characteristics and RTW in specific subgroups. Among the 3004 patients included, women living with a partner returned less to work (OR = 0.63 [0.47-0.86]) and decreased their working time after RTW. Among the 2305 women living with a partner, being married was associated with decreased RTW among women aged over 50 (OR = 0.57 [0.34-0.95]). Having three or more children (vs. none) was associated with lower RTW among women with low household income (OR = 0.28 [0.10-0.80]). Household characteristics should be considered in addition to clinical information to identify vulnerable women, reduce the social consequence of cancer and improve their quality of life.
乳腺癌康复后重返工作岗位（RTW）与生活质量改善相关。家庭特征与RTW之间的联系在很大程度上仍不为人知。本研究的目的是考察家庭状况对乳腺癌女性患者康复两年后重返工作岗位的影响。我们使用了一个法国前瞻性队列研究的数据，该队列研究的对象是被诊断为I - III期原发性乳腺癌的女性（CANTO，NCT01993498）。在诊断时就业且年龄在57岁以下的女性中，我们评估了家庭特征（与伴侣同住、婚姻状况、经济上依赖的子女数量和年龄、伴侣的支持）与RTW之间的关联。逻辑回归模型对年龄、家庭收入、癌症分期、合并症、治疗及其副作用进行了调整。进行了按年龄和家庭收入分层的分析，以评估特定亚组中家庭特征与RTW之间的关联。在纳入的3004名患者中，与伴侣同住的女性重返工作岗位的比例较低（比值比[OR]=0.63[0.47 - 0.86]），且康复后工作时间减少。在2305名与伴侣同住的女性中，已婚与50岁以上女性重返工作岗位的比例降低相关（OR = 0.57[0.34 - 0.95]）。家庭收入低的女性中，有三个或更多孩子（与没有孩子相比）与较低的重返工作岗位比例相关（OR = 0.28[0.10 - 0.80]）。除了临床信息外，还应考虑家庭特征，以识别脆弱女性，减少癌症的社会影响并改善她们的生活质量。
