Division of Physical Activity, Prevention and Cancer, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.
Division of Medical Oncology, University Clinic Heidelberg and National Center for Tumor Diseases (NCT), Heidelberg, Germany.
Eur J Cancer Care (Engl). 2019 Jul;28(4):e13051. doi: 10.1111/ecc.13051. Epub 2019 Apr 29.
For breast cancer survivors return to work (RTW) is important from an economic, societal and personal perspective. Thus, we investigated the impact of side effects and other factors on RTW. Five years post-diagnosis 135 disease-free breast cancer survivors below retirement age who were employed pre-diagnosis recorded their current and previous working status and reasons for impaired RTW. Patient-reported outcomes were prospectively reported over the cancer continuum. One year post-surgery 57% of survivors worked the same and 22% with reduced working time compared to pre-diagnosis. Logistic regression revealed significant associations of depressive symptoms, arm morbidity, lower education and younger age with impaired RTW after 1 year, and persisting physical fatigue and living with partner with impaired RTW after 5 years. Major self-reported reasons included fatigue and cognitive problems. Temporal patterns of general quality of life (QoL), physical, cognitive and role function, and financial problems were significantly worse among women with no RTW compared to those working again. In conclusion, cessation of work after breast cancer seems associated with worse QoL. Fatigue, psychological and cognitive problems as well as arm morbidity seemed to hinder RTW. Thus, a better management of these problems might help women to stay in working life.
对于乳腺癌幸存者来说，重返工作岗位（RTW）从经济、社会和个人角度来看都很重要。因此，我们研究了副作用和其他因素对 RTW 的影响。在诊断后 5 年内，135 名无病乳腺癌幸存者达到退休年龄以下，且在诊断前有工作，记录了他们目前和以前的工作状态以及 RTW 受损的原因。患者报告的结果在癌症连续体中进行了前瞻性报告。与诊断前相比，手术后 1 年，57%的幸存者从事相同工作，22%的幸存者工作时间减少。逻辑回归显示，抑郁症状、手臂发病、较低的教育程度和较年轻的年龄与 1 年后 RTW 受损显著相关，而持续的身体疲劳和与伴侣一起生活与 5 年后 RTW 受损相关。主要的自我报告原因包括疲劳和认知问题。与重新工作的女性相比，无 RTW 的女性一般生活质量（QoL）、身体、认知和角色功能以及财务问题的时间模式明显更差。总之，乳腺癌后停止工作似乎与 QoL 更差有关。疲劳、心理和认知问题以及手臂发病似乎阻碍了 RTW。因此，更好地管理这些问题可能有助于女性继续工作。
