山金车作为疼痛管理辅助药物的临床试验、潜在机制及不良反应
Clinical Trials, Potential Mechanisms, and Adverse Effects of Arnica as an Adjunct Medication for Pain Management.
作者信息
Smith Amanda G, Miles Victoria N, Holmes Deltrice T, Chen Xin, Lei Wei
机构信息
Department of Pharmaceutical and Administrative Sciences, Presbyterian College School of Pharmacy, Clinton, SC 29325, USA.
Department of Biology, College of Art and Sciences, Presbyterian College, Clinton, SC 29325, USA.
出版信息
Medicines (Basel). 2021 Oct 9;8(10):58. doi: 10.3390/medicines8100058.
Abstract
Arnica has traditionally been used in treating numerous medical conditions, including inflammation and pain. This review aims to summarize the results of studies testing Arnica products for pain management under different conditions, including post-operation, arthritis, low back pain, and other types of musculoskeletal pain. Based on data from clinical trials, Arnica extract or gel/cream containing Arnica extract shows promising effects for pain relief. These medical benefits of Arnica may be attributed to its chemical components, with demonstrated anti-inflammatory, antioxidant, anti-microbial, and other biological activities. In conclusion, Arnica could be an adjunct therapeutical approach for acute and chronic pain management.
摘要
山金车传统上一直用于治疗多种病症，包括炎症和疼痛。本综述旨在总结在不同情况下测试山金车产品用于疼痛管理的研究结果，这些情况包括术后、关节炎、腰痛以及其他类型的肌肉骨骼疼痛。基于临床试验数据，山金车提取物或含山金车提取物的凝胶/乳膏显示出有希望的止痛效果。山金车的这些医学益处可能归因于其化学成分，这些成分具有已证实的抗炎、抗氧化、抗菌及其他生物活性。总之，山金车可能是急性和慢性疼痛管理的一种辅助治疗方法。
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