State Committee of Veterinary and Livestock Development of the Republic of Uzbekistan, Tashkent, Uzbekistan.
Institute of Zoology of the Academy of Sciences of the Republic of Uzbekistan, Tashkent, Uzbekistan.
Parasitol Res. 2021 Dec;120(12):3987-3992. doi: 10.1007/s00436-021-07347-w. Epub 2021 Oct 22.
Among the zoonotic mosquito-borne nematodes, Dirofilaria repens and Dirofilaria immitis (Spirurida, Onchocercidae) are highly significant from a public health perspective. While D. immitis is also of major veterinary concern, D. repens is regarded as less pathogenic for carnivores, but is the main causative agent of human dirofilariosis throughout the Old World. In the Republic of Uzbekistan, recent data refer exclusively to D. immitis infection in domestic and wild carnivores, while the current prevalence and distribution of D. repens remain unknown. Between 2015 and 2021, a total of 559 domestic and wild carnivore carcasses were collected and examined by necropsy. All subcutaneous nematodes were collected and identified morphologically. The overall prevalence of D. repens infection was of 11.03% in domestic dogs, Canis familiaris, and 9.29% in wildlife hosts: golden jackals, Canis aureus (11.76%), wolves, Canis lupus (9.09%), red foxes, Vulpes vulpes (9.23%), and jungle cats, Felis chaus (7.14%). Additionally, a human case of subcutaneous D. repens infection was also documented. The present study represents the first recent assessment of the occurrence of the zoonotic filarioid D. repens in the Republic of Uzbekistan. It indicates a wide distribution in domestic dogs and four species of wildlife hosts throughout the country, raising awareness on the public health risks associated with this parasite.
在人畜共患的蚊媒线虫中，从公共卫生的角度来看，复孔绦虫和犬恶丝虫（旋尾目，恶丝虫科）非常重要。虽然犬恶丝虫也对兽医具有重大意义，但复孔绦虫对食肉动物的致病性较低，但它是旧世界人类丝虫病的主要病原体。在乌兹别克斯坦共和国，最近的数据仅涉及国内和野生食肉动物的犬恶丝虫感染，而目前复孔绦虫的流行情况和分布情况尚不清楚。2015 年至 2021 年，共采集并通过剖检检查了 559 只家养和野生食肉动物尸体。所有皮下线虫均通过形态学收集和鉴定。家养犬（犬属）的复孔绦虫感染总流行率为 11.03%，野生动物宿主的流行率为 9.29%：金豺（犬属）为 11.76%、狼（犬属）为 9.09%、红狐（狐属）为 9.23%、丛林猫（猫属）为 7.14%。此外，还记录了一例人体皮下复孔绦虫感染病例。本研究代表了对乌兹别克斯坦共和国人畜共患的复孔绦虫流行情况的首次最新评估。它表明该寄生虫在国内犬和四种野生动物宿主中广泛分布，提高了人们对与这种寄生虫相关的公共卫生风险的认识。
