通过原位杂交将胃蛋白酶原基因复合体（PGA）定位于人类染色体区域11q13。
Assignment of the pepsinogen gene complex (PGA) to human chromosome region 11q13 by in situ hybridization.
作者信息
Nakai H, Byers M G, Shows T B, Taggart R T
出版信息
Cytogenet Cell Genet. 1986;43(3-4):215-7. doi: 10.1159/000132324.
PMID:3467902
Abstract
The genes coding for human pepsinogen (PGA3, PGA4, and PGA5) were assigned to chromosome region 11q13 by in situ hybridization. Previously we localized the PGA gene complex to a centromeric region of chromosome 11 (p11----q13) by Southern blot analysis of mouse-human somatic cell hybrids. Our in situ hybridization results confirm this assignment and further localize the genes to a smaller region on the long arm.
摘要
通过原位杂交技术，编码人胃蛋白酶原（PGA3、PGA4和PGA5）的基因被定位到染色体区域11q13。此前，我们通过对小鼠-人类体细胞杂种进行Southern印迹分析，将PGA基因复合体定位到染色体11的着丝粒区域（p11----q13）。我们的原位杂交结果证实了这一定位，并进一步将这些基因定位到长臂上一个更小的区域。
Zotero 插件