LAQV, REQUIMTE, Departamento de Ciências Químicas, Faculdade de Farmácia da Universidade do Porto, 4050-313 Porto, Portugal.
Biomolecules. 2021 Oct 15;11(10):1518. doi: 10.3390/biom11101518.
Hyaluronic acid (HA) is a natural polymer, produced endogenously by the human body, which has unique physicochemical and biological properties, exhibiting desirable biocompatibility and biodegradability. Therefore, it has been widely studied for possible applications in the area of inflammatory diseases. Although exogenous HA has been described as unable to restore or replace the properties and activities of endogenous HA, it can still provide satisfactory pain relief. This review aims to discuss the advances that have been achieved in the treatment of inflammatory diseases using hyaluronic acid as a key ingredient, essentially focusing on studies carried out between the years 2017 and 2021.
透明质酸（HA）是一种天然聚合物，由人体自身产生，具有独特的物理化学和生物学特性，表现出良好的生物相容性和可降解性。因此，它已被广泛研究用于炎症性疾病的可能应用。尽管外源性 HA 已被描述为不能恢复或替代内源性 HA 的特性和活性，但它仍然可以提供令人满意的止痛效果。本综述旨在讨论使用透明质酸作为关键成分治疗炎症性疾病方面所取得的进展，主要集中在 2017 年至 2021 年期间进行的研究。
