Al Tabaa Yassine, Bailly Clement, Kanoun Salim
Scintidoc Nuclear Medicine Center, 25 rue de Clémentville, 34070 Montpellier, France.
CRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, 44093 Nantes, France.
Cancers (Basel). 2021 Oct 18;13(20):5222. doi: 10.3390/cancers13205222.
18F-fluorodeoxyglucose positron emission tomography combined with computed tomography (FDG-PET/CT) is an essential part of the management of patients with lymphoma at staging and response evaluation. Efforts to standardize PET acquisition and reporting, including the 5-point Deauville scale, have enabled PET to become a surrogate for treatment success or failure in common lymphoma subtypes. This review summarizes the key clinical-trial evidence that supports PET-directed personalized approaches in lymphoma but also points out the potential place of innovative PET/CT metrics or new radiopharmaceuticals in the future.
18F-氟脱氧葡萄糖正电子发射断层扫描联合计算机断层扫描(FDG-PET/CT)是淋巴瘤患者分期和疗效评估管理的重要组成部分。包括五点迪厄多内量表在内的标准化PET采集和报告工作,使PET成为常见淋巴瘤亚型治疗成败的替代指标。本综述总结了支持淋巴瘤中PET导向个性化方法的关键临床试验证据,但也指出了创新的PET/CT指标或新型放射性药物在未来的潜在地位。