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微创脊柱减压术与开放椎板切除术联合融合治疗腰椎管狭窄症的长期疼痛特征和管理。

Long-Term Pain Characteristics and Management Following Minimally Invasive Spinal Decompression and Open Laminectomy and Fusion for Spinal Stenosis.

机构信息

The Department of Neurosurgery, Tel-Aviv Sourasky Medical Center, Tel Aviv 6423906, Israel.

Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.

出版信息

Medicina (Kaunas). 2021 Oct 18;57(10):1125. doi: 10.3390/medicina57101125.

Abstract

: To compare the long-term pain characteristics and its chronic management following minimally invasive spinal (MIS) decompression and open laminectomy with fusion for lumbar stenosis. : The study cohort included patients with a minimum 5-year postoperative follow-up after undergoing either MIS decompression or laminectomy with fusion for spinal claudication. The primary outcome of interest was chronic back and leg pain intensity. Secondary outcome measures included pain frequency during the day, chronic use of non-opioid analgesics, narcotic medications, medical cannabinoids, and continuous interventional pain treatments. : A total of 95 patients with lumbar spinal stenosis underwent one- or two-level surgery for lumbar spinal stenosis between April 2009 and July 2013. Of these, 50 patients underwent MIS decompression and 45 patients underwent open laminectomy with instrumented fusion. In the fusion group, a higher percentage of patients experienced moderate-to-severe back pain with 48% compared to 21.8% of patients in the MIS decompression group ( < 0.01). In contrast, we found no significant difference in the reported leg pain in both groups. In the fusion group, 20% of the patients described their back and leg pain as persistent throughout the day compared to only 2.2% in the MIS decompression group ( < 0.05). A trend toward higher chronic dependence on analgesic medication and repetitive pain clinic treatments was found in the fusion group. : MIS decompression for the treatment of degenerative spinal stenosis resulted in decreased long-term back pain and similar leg pain outcomes compared to open laminectomy and instrumented fusion surgery.

摘要

比较微创脊柱减压术 (MIS) 和开放性椎板切除术联合融合术治疗腰椎狭窄症的长期疼痛特征及其慢性管理。

该研究队列包括接受微创减压或椎板切除术联合融合术治疗脊柱狭窄症的患者,术后至少有 5 年的随访。主要观察指标为慢性腰背疼痛强度。次要观察指标包括白天疼痛频率、慢性使用非阿片类镇痛药、阿片类药物、医用大麻和连续介入性疼痛治疗。

共有 95 例腰椎管狭窄症患者于 2009 年 4 月至 2013 年 7 月行单或双节段手术治疗腰椎管狭窄症。其中,50 例行 MIS 减压,45 例行开放性椎板切除术联合器械融合术。在融合组中,更多的患者经历了中重度腰痛,为 48%,而 MIS 减压组为 21.8%(<0.01)。相比之下,我们发现两组患者报告的腿部疼痛无显著差异。在融合组中,20%的患者描述他们的腰背疼痛整天持续存在,而 MIS 减压组仅为 2.2%(<0.05)。融合组患者对镇痛药物和重复疼痛诊所治疗的慢性依赖呈上升趋势。

MIS 减压治疗退行性脊柱狭窄症可降低长期背痛,并获得与开放性椎板切除术联合器械融合术相似的腿部疼痛结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/07c8/8539437/755b5d95e490/medicina-57-01125-g001.jpg

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