Yoo Jeong-Rae, Kim Mi-Sun, Heo Sang-Taek, Oh Hyun-Joo, Oh Jung-Hwan, Ko Seo-Young, Kang Jeong-Ho, Lee Sung-Kgun, Jeong Woo-Seong, Seong Gil-Myeong, Lee Hyun-Jung, Kang Chul-Hoo, Moon Ji-Hyun, Lee Keun-Hwa, Song Sung-Wook
Department of Internal Medicine, College of Medicine, Jeju National University, Jeju 63241, Korea.
Center for Farmers' Safety and Health, Jeju National University Hospital, Jeju 63241, Korea.
Pathogens. 2021 Oct 17;10(10):1337. doi: 10.3390/pathogens10101337.
infects humans and wild and domesticated animals. Although reported cases on Jeju Island, off the coast of South Korea, are rare, the region is considered to have a high potential for Q fever. We investigated the seroprevalence of antibodies to in 230 farmers living in ten rural areas on Jeju Island between January 2015 and December 2019. Blood samples were collected and examined for Phase I/II IgM and IgG antibodies. Trained researchers collected ticks from rural areas. Clone XCP-1 16S ribosomal RNA gene sequencing was performed to identify species from the collected ticks. The overall seroprevalence of antibodies to in farmers was 35.7%. The seroprevalence was significantly higher in fruit farmers. Of the collected ticks, 5.4% (19/351) of the ticks harbored A high seroprevalence of antibodies to was observed in this region of Jeju Island, confirming that is endemic. Physicians should thus consider Q fever in the differential diagnosis of patients that present with acute fever after participating in outdoor activities.
感染人类以及野生和家养动物。尽管韩国海岸外济州岛的报告病例很少，但该地区被认为有很高的Q热发病可能性。我们调查了2015年1月至2019年12月期间居住在济州岛十个农村地区的230名农民中抗[病原体名称未给出]抗体的血清阳性率。采集血样并检测[病原体名称未给出]I/II期IgM和IgG抗体。训练有素的研究人员从农村地区采集蜱虫。进行克隆XCP - 1 16S核糖体RNA基因测序以从采集的蜱虫中鉴定[病原体名称未给出]物种。农民中抗[病原体名称未给出]抗体的总体血清阳性率为35.7%。果农的血清阳性率显著更高。在采集的蜱虫中，5.4%（19/351）的[蜱虫名称未给出]蜱虫携带[病原体名称未给出]。在济州岛的该地区观察到抗[病原体名称未给出]抗体的高血清阳性率，证实[病原体名称未给出]为地方病。因此，医生在对参加户外活动后出现急性发热的患者进行鉴别诊断时应考虑Q热。
