Gastrointestinal Unit, Department of Translational Sciences and New Technologies in Medicine and Surgery, University of Pisa, 56124 Pisa, Italy.
Clinical and Experimental Medicine-Rheumatology Unit, University of Pisa, 56100 Pisa, Italy.
Nutrients. 2021 Sep 26;13(10):3386. doi: 10.3390/nu13103386.
Chronic constipation (CC) is one of the most common gastroenterological diagnoses in clinical practice. Treatment includes several steps, depending on the severity of symptoms. Lifestyle modifications and increased intake of fiber and water are suggested by most health professionals. Unfortunately, the recommendations in this regard are the most varied, often conflicting with each other and not always based on solid scientific arguments. This paper aims to clarify this topic by providing practical indications for the management of these patients in every day clinical practice. The literature available on this topic is scarce, and dietary studies have important methodological biases. However, fiber, mainly by binding water and acting as bulking agents and/or as prebiotics for the intestinal microbiota, and mineral water, especially if rich in magnesium and/or bicarbonate, are useful tools. An adequate, well-designed diet should be a cornerstone of any effective treatment for chronic constipation. High-quality studies on larger samples are mandatory to give scientific validity to the role of the food in CC therapy and to enable professionals to choose the best approach for their patients, combining nutritional and pharmacological agents.
慢性便秘(CC)是临床实践中最常见的胃肠道诊断之一。治疗包括几个步骤,具体取决于症状的严重程度。大多数健康专家建议改变生活方式,并增加纤维和水的摄入。不幸的是,在这方面的建议是最多种多样的,往往相互矛盾,并不总是基于坚实的科学论据。本文旨在通过为每位患者在日常临床实践中提供实用的管理这些患者的指示来澄清这一主题。关于这个主题的文献很少,饮食研究存在重要的方法学偏见。然而,纤维主要通过结合水并作为膨松剂和/或作为肠道微生物群的益生元,以及矿泉水,特别是如果富含镁和/或碳酸氢盐,是有用的工具。充足、精心设计的饮食应该是任何慢性便秘有效治疗的基石。需要进行高质量的、更大样本量的研究,以赋予食物在 CC 治疗中的作用以科学依据,并使专业人员能够为患者选择最佳的方法,结合营养和药物治疗。