Nutrigenomics Research Group, Departament de Bioquímica i Biotecnologia, Universitat Rovira i Virgili, 43007 Tarragona, Spain.
Nutrients. 2021 Oct 18;13(10):3643. doi: 10.3390/nu13103643.
The phytochemical composition of fruits, especially polyphenols, depends on the environmental conditions under which these fruits are cultivated and the agronomic practices followed. Therefore, the consumption of fruits from different origins, with different polyphenol signatures, could have differential effects on health. In addition, recent studies have shown that variation in the biological rhythms due to changes in the photoperiod in the different seasons differentially affect the metabolism in animal models, thus conditioning their response to food consumption. Considering all, this article evaluates the effects of consumption of sweet cherry from different sources, local (LC) and non-local (nLC), on plasma metabolic parameters and the gene expression of key enzymes of lipid metabolism in Fischer 344 rats under photoperiods simulating different seasons. Animals were classified into three photoperiods (L6, L12 and L18) and three treatments (LC, nLC and VH). Both the photoperiod and the treatments significantly affected the evaluated parameters. An effect of the photoperiod on triacylglycerides, non-esterified fatty acids and the mRNA concentration of crucial enzymes from the hepatic lipid metabolism was observed. Furthermore, the consumption of fruit in L12 lowered blood glucose, while the different treatments affected the hepatic expression of genes related with lipidic enzymes.
水果的植物化学成分，特别是多酚类物质，取决于这些水果生长的环境条件和采用的农业实践。因此，食用来自不同产地、具有不同多酚特征的水果可能对健康产生不同的影响。此外，最近的研究表明，由于不同季节中光周期的变化导致的生物节律的变化会使动物模型的代谢产生差异，从而影响它们对食物摄入的反应。综上所述，本文评估了食用来自不同来源（本地[LC]和非本地[nLC]）的甜樱桃对光照周期模拟不同季节的 Fischer 344 大鼠血浆代谢参数和关键脂质代谢酶基因表达的影响。动物被分为三个光照周期（L6、L12 和 L18）和三个处理组（LC、nLC 和 VH）。光照周期和处理都显著影响了评估参数。光照周期对三酰甘油、非酯化脂肪酸和肝脏脂质代谢关键酶的 mRNA 浓度有影响。此外，在 L12 光照周期下食用水果可降低血糖，而不同的处理则影响与脂质酶相关的基因在肝脏中的表达。
