体重增加与儿童和青少年的 COVID-19 封锁相关：系统评价和荟萃分析。

Weight Gain Associated with COVID-19 Lockdown in Children and Adolescents: A Systematic Review and Meta-Analysis.

机构信息

Department of Pediatrics, Chi Mei Medical Center, Tainan 71004, Taiwan.

Department of Pediatrics, Chi Mei Medical Center, Chiali, Tainan 72263, Taiwan.

出版信息

Nutrients. 2021 Oct 19;13(10):3668. doi: 10.3390/nu13103668.

BACKGROUND

Lockdown is an effective nonpharmaceutical intervention to reduce coronavirus disease 2019 (COVID-19) transmission, but it restricts daily activity. We aimed to investigate the impact of lockdown on pediatric body weight and body mass index (BMI).

METHODS

The systematic review and meta-analysis were conducted following the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) statement. Four online databases (EMBASE, Medline, the Cochrane Library and CINAHL) were searched.

RESULTS

The pooled results showed that lockdown was associated with significant body weight gain (MD 2.67, 95% CI 2.12-3.23; < 0.00001). The BMI of children with comorbidities or obesity did not change significantly. The BMI of general population was significantly higher during lockdown than before the pandemic (MD 0.94, 95% CI 0.32-1.56; = 0.003). However, heterogeneity was high (I = 84%). Among changes in weight classification, increases in the rates of obesity (OR 1.23, 95% CI 1.10-1.37; = 0.0002) and overweight (OR 1.17, 95% CI 1.06-1.29; = 0.001) were reported.

CONCLUSIONS

Our meta-analysis showed significant increases in body weight and BMI during lockdown among school-age children and adolescents. The prevalence of obesity and overweight also increased. The COVID-19 pandemic worsened the burden of childhood obesity.

背景

封锁是减少 2019 年冠状病毒病（COVID-19）传播的有效非药物干预措施，但它限制了日常活动。我们旨在调查封锁对儿科体重和体重指数（BMI）的影响。

方法

系统评价和荟萃分析遵循系统评价和荟萃分析的首选报告项目（PRISMA）声明进行。四个在线数据库（EMBASE、Medline、Cochrane 图书馆和 CINAHL）进行了搜索。

结果

汇总结果表明，封锁与体重显著增加相关（MD 2.67，95%CI 2.12-3.23；<0.00001）。患有合并症或肥胖症的儿童的 BMI 没有明显变化。与大流行前相比，普通人群在封锁期间的 BMI 明显更高（MD 0.94，95%CI 0.32-1.56；=0.003）。然而，异质性很高（I=84%）。在体重分类的变化中，肥胖（OR 1.23，95%CI 1.10-1.37；=0.0002）和超重（OR 1.17，95%CI 1.06-1.29；=0.001）的发生率增加。