Bisogno Antonella, Scarpa Alfonso, Di Girolamo Stefano, De Luca Pietro, Cassandro Claudia, Viola Pasquale, Ricciardiello Filippo, Greco Antonio, Vincentiis Marco De, Ralli Massimo, Di Stadio Arianna
Department of Otolaryngology, University of Salerno, 84125 Salerno, Italy.
Department of Otolaryngology, Tor Vergata University, 00133 Roma, Italy.
Life (Basel). 2021 Oct 17;11(10):1102. doi: 10.3390/life11101102.
In recent years, there has been increasing research interest in the correlation between hearing impairment and cognitive decline, two conditions that have demonstrated a strong association. Hearing loss appears as a risk factor for cognitive impairment, especially among certain populations, notably nursing home residents. Furthermore, hearing loss has been identified as a modifiable age-related condition linked to dementia, and it has been estimated that midlife hearing loss, if eliminated, might decrease the risk of dementia in the general population. Several mechanisms have been suggested to explain the pathologic connections between hearing loss and dementia; however, clear evidence is missing, and the common pathophysiological basis is still unclear. In this review, we discussed current knowledge about the relationship between hearing loss and dementia, and future perspectives in terms of the effects of hearing rehabilitation for early prevention of cognitive decline.
近年来,听力障碍与认知衰退之间的相关性引发了越来越多的研究兴趣,这两种情况已显示出密切联系。听力损失似乎是认知障碍的一个风险因素,尤其是在某些人群中,特别是养老院居民。此外,听力损失已被确定为一种与痴呆症相关的可改变的年龄相关病症,据估计,如果消除中年听力损失,可能会降低普通人群患痴呆症的风险。已经提出了几种机制来解释听力损失与痴呆症之间的病理联系;然而,缺乏明确的证据,共同的病理生理基础仍不清楚。在这篇综述中,我们讨论了关于听力损失与痴呆症关系的现有知识,以及听力康复对早期预防认知衰退影响方面的未来前景。