静磁场对口腔组织来源细胞的生物效应评价及其在再生医学中的应用。
The Review of Bioeffects of Static Magnetic Fields on the Oral Tissue-Derived Cells and Its Application in Regenerative Medicine.
机构信息
School of Dentistry, Collage of Oral Medicine, Taipei Medical University, Taipei 11031, Taiwan.
Department of Dentistry, Division of Prosthodontics, Taipei Medical University Hospital, Taipei 11031, Taiwan.
出版信息
Cells. 2021 Oct 5;10(10):2662. doi: 10.3390/cells10102662.
Magnets have been widely used in dentistry for orthodontic tooth movement and denture retention. Nevertheless, criticisms have arisen regarding the biosafety of static magnetic field (SMF) effects on surrounding tissues. Various controversial pieces of evidence have been discussed regarding SMFs on cellular biophysics, but little consensus has been reached, especially in the field of dentistry. Thus, the present paper will first review the safe use of SMFs in the oral cavity and as an additive therapy to orthodontic tooth movement and periodontium regeneration. Then, studies regarding SMF-incorporated implants are reviewed to investigate the advantageous effects of SMFs on osseointegration and the underlying mechanisms. Finally, a review of current developments in dentistry surrounding the combination of magnetic nanoparticles (MNPs) and SMFs is made to clarify potential future clinical applications.
磁铁在牙齿矫正和义齿固位方面已被广泛应用于牙科领域。然而，人们对静磁场（SMF）对周围组织的生物安全性提出了批评。关于 SMF 对细胞生物物理学的影响，已经讨论了各种有争议的证据，但尚未达成共识，尤其是在牙科领域。因此，本文首先将回顾 SMF 在口腔内的安全使用情况，以及作为正畸牙齿移动和牙周组织再生的附加治疗方法。然后，回顾了关于含有 SMF 的植入物的研究，以研究 SMF 对骨整合的有利影响及其潜在机制。最后，对当前围绕磁性纳米粒子（MNPs）和 SMF 组合的牙科领域的最新发展进行综述，以阐明潜在的未来临床应用。
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