Research & Development Institute of Northwestern Polytechnical University in Shenzhen, Shenzhen, 518057, China; School of Life Science, Northwestern Polytechnical University, Xi'an, Shaanxi, 710072, China; Key Laboratory for Space Bioscience and Biotechnology, Institute of Special Environmental Biophysics, Northwestern Polytechnical University, Xi'an, 710072, China.
Research & Development Institute of Northwestern Polytechnical University in Shenzhen, Shenzhen, 518057, China; School of Life Science, Northwestern Polytechnical University, Xi'an, Shaanxi, 710072, China; Key Laboratory for Space Bioscience and Biotechnology, Institute of Special Environmental Biophysics, Northwestern Polytechnical University, Xi'an, 710072, China; Yangtze River Delta Research Institute of Northwestern Polytechnical University, Taicang, 215400, China.
Prog Biophys Mol Biol. 2023 Jan;177:14-23. doi: 10.1016/j.pbiomolbio.2022.09.002. Epub 2022 Oct 12.
With the widespread use of static magnetic fields (SMFs) in medicine, it is imperative to explore the biological effects of SMFs and the mechanisms underlying their effects on biological systems. The presence of magnetic materials within cells and organisms could affect various biological metabolism and processes, including stress responses, proliferation, and structural alignment. SMFs were generally found to be safe at the organ and organism levels. However. human subjects exposed to strong SMFs have reported side effects. In this review, we combined the magnetic properties of biological samples to illustrate the mechanism of action of SMFs on biological systems from a biophysical point of view. We suggest that the mechanisms of action of SMFs on biological systems mainly include the induction of electric fields and currents, generation of magnetic effects, and influence of electron spins. An electrolyte flowing in a static magnetic field generates an induced current and an electric field. Magnetomechanical effects include orientation effects upon subjecting biological samples to SMFs and movement of biological samples in strong field gradients. SMFs are thought to affect biochemical reaction rates and yields by influencing electron spin. This paper helps people how can harness the favorable biological effects of SMFs.
随着静磁场（SMFs）在医学中的广泛应用，探索 SMFs 的生物学效应及其对生物系统影响的机制势在必行。细胞和生物体内的磁性材料可能会影响各种生物代谢和过程，包括应激反应、增殖和结构排列。在器官和生物体水平上，通常发现 SMFs 是安全的。然而，暴露于强 SMFs 的人体报告了副作用。在这篇综述中，我们结合生物样本的磁性特性，从生物物理的角度说明了 SMFs 对生物系统的作用机制。我们认为，SMFs 对生物系统的作用机制主要包括感应电场和电流的产生、磁效应的产生以及电子自旋的影响。在静态磁场中流动的电解质会产生感应电流和电场。磁力学效应包括将生物样本置于 SMFs 下的取向效应以及在强磁场梯度中生物样本的运动。SMFs 被认为通过影响电子自旋来影响生化反应速率和产率。本文有助于人们利用 SMFs 的有利生物学效应。
