泰国一家三级医院儿科人群葡萄膜炎的发病模式。

The Pattern of Uveitis in a Pediatric Population at a Tertiary Center in Thailand.

机构信息

Department of Ophthalmology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand.

Epidemiology Unit, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand.

出版信息

Ocul Immunol Inflamm. 2023 Jan;31(1):56-64. doi: 10.1080/09273948.2021.1980814. Epub 2021 Oct 22.

DOI:10.1080/09273948.2021.1980814

PMID:34686121

Abstract

PURPOSE

To describe the clinical characteristics and longitudinal pattern of visual acuity (VA) of pediatric patients with uveitis at a tertiary center in Thailand.

METHODS

We retrospectively reviewed the records of children with uveitis ≤16 years who presented to the clinic between January 2010 and June 2020.

RESULTS

The mean age at onset was 9.1(±4.3) years; the main characteristics were chronic (64.4%), unilateral (68.6%), and panuveitis (39%). The common etiologies were ocular toxoplasmosis (11.9%), herpetic uveitis (10.2%), and ocular toxocariasis (6.8%). Further, 40% of the eyes presented with VA of ≤20/200; mean VA at baseline improved from 0.93 to 0.72 logMAR at 3 months after presentation ( < .001), the baseline VA of ≤20/200 was significantly associated with poor VA outcome at 1 year.

CONCLUSION

Chronic, unilateral, and panuveitis represented the majority of our children with uveitis. Infectious etiology was common. Significant VA improvement can be achieved with optimum management.

摘要

目的

描述泰国一家三级医院儿科葡萄膜炎患者的临床特征和视力（VA）的纵向变化模式。

方法

我们回顾性分析了 2010 年 1 月至 2020 年 6 月期间在诊所就诊的≤16 岁儿童葡萄膜炎患者的病历。

结果

发病时的平均年龄为 9.1（±4.3）岁；主要特征为慢性（64.4%）、单侧（68.6%）和全葡萄膜炎（39%）。常见病因是眼弓蛔虫病（6.8%）、眼弓形虫病（11.9%）和疱疹性葡萄膜炎（10.2%）。此外，40%的眼 VA≤20/200；基线时的平均 VA 从就诊后 3 个月的 0.93 改善到 0.72 logMAR（<0.001），基线 VA≤20/200 与 1 年后的不良 VA 结局显著相关。