Waduthantri Samanthila, Chee Soon-Phaik
Singapore Eye Research Institute, Singapore, Singapore.
Department of Ocular Inflammation & Immunology, Singapore National Eye Centre, Singapore, Singapore.
Ocul Immunol Inflamm. 2021 Nov 17;29(7-8):1304-1311. doi: 10.1080/09273948.2020.1766083. Epub 2020 Jul 9.
: To describe the demographics and clinical characteristics of pediatric uveitis and scleritis at a tertiary eye care center.: Clinical records of children with either uveitis or scleritis that presented between January 1989 and January 2016 were reviewed retrospectively.: Seventy-three patients were identified. Fifty-four had uveitis and 19 had scleritis. Posterior uveitis was the most common (27.8%), followed by intermediate uveitis (25.9%), panuveitis (25.9%) and anterior uveitis. Majority were noninfectious uveitis (37.0%), and 29.6% were idiopathic. Common associations were sarcoidosis (14.8%), HLA-B27 haplotype (9.3%) and toxoplasmosis (7.4%). Posterior scleritis was more common (94.7%) than anterior scleritis and majority were idiopathic (68.4%). Delayed patient presentation and presenting visual acuity worse than 0.3 LogMAR were associated with poor visual outcome ( = .03; OR = 0.17; 95% CI, 0.03-0.84 and = .007; OR = 0.09; 95% CI, 0.02-0.52 respectively).: Majority had noninfectious etiologies. Uveitis associated with juvenile idiopathic arthritis was rare.
描述一家三级眼科护理中心小儿葡萄膜炎和巩膜炎的人口统计学特征及临床特点。
回顾性分析1989年1月至2016年1月期间就诊的葡萄膜炎或巩膜炎患儿的临床记录。
共确定73例患者。其中54例为葡萄膜炎，19例为巩膜炎。后葡萄膜炎最常见（27.8%），其次是中间葡萄膜炎（25.9%）、全葡萄膜炎（25.9%）和前葡萄膜炎。多数为非感染性葡萄膜炎（37.0%），29.6%为特发性。常见相关因素有结节病（14.8%）、HLA - B27单倍型（9.3%）和弓形虫病（7.4%）。后巩膜炎比前巩膜炎更常见（94.7%），多数为特发性（68.4%）。患者就诊延迟及就诊时视力低于0.3 LogMAR与视力预后不良相关（分别为P = 0.03；OR = 0.17；95% CI，0.03 - 0.84和P = 0.007；OR = 0.09；95% CI，0.02 - 0.52）。
多数病因是非感染性的。与幼年特发性关节炎相关的葡萄膜炎罕见。
