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Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332.

作者信息

Zhao Yao, Fang Chao, Zhang Qi, Zhang Ruxue, Zhao Xiangbo, Duan Yinkai, Wang Haofeng, Zhu Yan, Feng Lu, Zhao Jinyi, Shao Maolin, Yang Xiuna, Zhang Leike, Peng Chao, Yang Kailin, Ma Dawei, Rao Zihe, Yang Haitao

机构信息

Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.

State Key Laboratory of Bioorganic & Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200032, China.

出版信息

Protein Cell. 2022 Sep;13(9):689-693. doi: 10.1007/s13238-021-00883-2. Epub 2021 Oct 22.

DOI:10.1007/s13238-021-00883-2
PMID:34687004
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8533666/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bed/9233717/3bae559a254c/13238_2021_883_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bed/9233717/3bae559a254c/13238_2021_883_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bed/9233717/3bae559a254c/13238_2021_883_Fig1_HTML.jpg

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Resurgence of SARS-CoV-2 Infection in a Highly Vaccinated Health System Workforce.在高度接种疫苗的医疗系统工作人员中出现的新冠病毒感染复发现象。
N Engl J Med. 2021 Sep 30;385(14):1330-1332. doi: 10.1056/NEJMc2112981. Epub 2021 Sep 1.
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Progress of the COVID-19 vaccine effort: viruses, vaccines and variants versus efficacy, effectiveness and escape.
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