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乳腺化生性鳞状细胞癌的超声及病理特征:病例系列研究。

Sonographic and pathological features of metaplastic squamous cell carcinoma of the breast: a case series.

机构信息

Department of Ultrasound, The First Affiliated Hospital of Fujian Medical University, 20 Chazhong Road, Fuzhou, 350005, China.

Department of Urology, Urology Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.

出版信息

BMC Surg. 2021 Oct 23;21(1):374. doi: 10.1186/s12893-021-01375-0.

DOI:10.1186/s12893-021-01375-0
PMID:34688286
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8540098/
Abstract

OBJECTIVE

The aim of this study was to evaluate the sonographic features and to compare the sonographic findings with the pathologic features.

METHODS

The sonographic and pathological features of all patients were retrospectively reviewed.

RESULTS

All these 9 patients presented with a palpable breast mass first found by the patient before presentation. The median diameters were 3.67 cm. On two-dimensional imaging, 8 masses showed mixed echogenicity with both solid and cystic components, and only 1 mass showed hypoechoic. All the masses had irregular shapes. 1 mass had indistinct margin and 8 masses had microlobulated margins. Calcifications was seen in 1 mass. On color Doppler flow imaging, 8 masses had high vascularity with high resistance index; 5 masses had grade III blood flow signal; 3 masses had grade II blood flow signal. On histopathological examination, 5 masses were adenocarcinoma with squamous metaplasia, and 4 masses were pure SCC. On immunohistochemical staining, estrogen receptors (ER), progesterone receptors (PR) and human epidermal growth factor receptor (HER2) were negative in 5 masses. There were 2 patients with lymph node metastasis.

CONCLUSIONS

Most of the sonographic features of MSCC were mixed echogenicity with central cystic components, posterior echo enhancement, abundant vascularity with high resistance.

摘要

目的

本研究旨在评估黏液表皮样癌(MSCC)的超声特征,并将其与病理特征进行比较。

方法

回顾性分析所有患者的超声和病理特征。

结果

所有患者均以触及乳腺肿块为首发表现,其中位直径为 3.67cm。二维成像显示,8 个肿块呈混合回声,既有实性成分又有囊性成分,仅 1 个肿块呈低回声。所有肿块均呈不规则形状,1 个肿块边界不清,8 个肿块边界呈细分叶状。1 个肿块内可见钙化。彩色多普勒血流成像显示,8 个肿块血流丰富,阻力指数较高;5 个肿块血流信号为Ⅲ级,3 个肿块血流信号为Ⅱ级。组织病理学检查显示,5 个肿块为伴有鳞状化生的腺癌,4 个肿块为单纯 SCC。免疫组化染色显示,5 个肿块的雌激素受体(ER)、孕激素受体(PR)和人表皮生长因子受体(HER2)均为阴性。有 2 例患者发生淋巴结转移。

结论

MSCC 的大多数超声特征为混合回声,中央有囊性成分,后方回声增强,血流丰富,阻力较高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75c/8540098/0e24374cd310/12893_2021_1375_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75c/8540098/9087a88f1f2f/12893_2021_1375_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75c/8540098/0e24374cd310/12893_2021_1375_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75c/8540098/9087a88f1f2f/12893_2021_1375_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75c/8540098/0e24374cd310/12893_2021_1375_Fig2_HTML.jpg

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本文引用的文献

1
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J Coll Physicians Surg Pak. 2018 Oct;28(10):776-778.
2
Clinical features and treatment of squamous cell carcinoma of the breast.乳腺鳞状细胞癌的临床特征与治疗
Onco Targets Ther. 2016 May 27;9:3181-5. doi: 10.2147/OTT.S95128. eCollection 2016.
3
[Clinicopathological features and prognostic factors of 22 cases of primary squamous cell carcinoma of the breast].22例原发性乳腺鳞状细胞癌的临床病理特征及预后因素
伴有骨肉瘤分化的乳腺化生性癌:一例报告及文献复习
Clin Pathol. 2022 Aug 25;15:2632010X221118056. doi: 10.1177/2632010X221118056. eCollection 2022 Jan-Dec.
Zhonghua Zhong Liu Za Zhi. 2015 Apr;37(4):293-6.
4
Metaplastic breast carcinoma: more than a special type.化生性乳腺癌:不只是一种特殊类型。
Nat Rev Cancer. 2014 Mar;14(3):147-8. doi: 10.1038/nrc3637.
5
Clinicopathologic characteristics and prognosis of primary squamous cell carcinoma of the breast.乳腺原发性鳞状细胞癌的临床病理特征及预后
Breast Cancer Res Treat. 2015 Jan;149(1):133-40. doi: 10.1007/s10549-014-3224-z. Epub 2014 Dec 5.
6
BI-RADS update.乳腺影像报告和数据系统(BI-RADS)更新。
Radiol Clin North Am. 2014 May;52(3):481-7. doi: 10.1016/j.rcl.2014.02.008.
7
Squamous cell carcinoma of the breast.乳腺鳞状细胞癌
Eur J Obstet Gynecol Reprod Biol. 2008 Apr;137(2):222-6. doi: 10.1016/j.ejogrb.2007.03.021. Epub 2007 May 3.
8
[A resected case of squamous cell carcinoma of the breast successfully treated by FU plus cisplatin (CDDP) adjuvant therapy against recurrent metastases].[1例乳腺鳞状细胞癌切除病例经氟尿嘧啶联合顺铂辅助治疗成功控制复发转移]
Gan To Kagaku Ryoho. 2007 Mar;34(3):443-6.
9
Differential immunohistochemical and biological profile of squamous cell carcinoma of the breast.乳腺鳞状细胞癌的免疫组织化学及生物学特征差异
Anticancer Res. 2007 Jan-Feb;27(1B):547-55.
10
Squamous cell carcinoma of the breast in the form of an intracystic tumor.呈囊内肿瘤形式的乳腺鳞状细胞癌。
Breast Cancer. 2007;14(1):109-12. doi: 10.2325/jbcs.14.109.