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老年人减重围手术期结局的种族差异。

Racial disparities in bariatric perioperative outcomes among the elderly.

机构信息

Department of General Surgery, Mayo Clinic, Jacksonville, Florida.

Department of Surgery, Temple University Hospital, Philadelphia, Pennsylvania.

出版信息

Surg Obes Relat Dis. 2022 Jan;18(1):62-70. doi: 10.1016/j.soard.2021.09.012. Epub 2021 Sep 29.

Abstract

BACKGROUND

Bariatric surgery outcomes in elderly patients have been shown to be safe, but with a higher rate of adverse outcomes compared with nonelderly patients. The impact of race on bariatric surgery outcomes continues to be explored, with recent studies showing higher rates of adverse outcomes in black patients. Perioperative outcomes in racial cohorts of elderly bariatric patients are largely unexplored.

OBJECTIVE

The goal of this study was to compare outcomes between elderly non-Hispanic black (NHB) and non-Hispanic white (NHW) bariatric surgery patients to determine whether outcomes are mediated by race.

SETTING

Academic hospital.

METHODS

Patients who had a primary Roux-en-Y (RYGB) and sleeve gastrectomy (SG) in the period 2015-2018 and were at least 65 years of age were identified from the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program Participant Use Data File (MBSAQIP PUF). Selected cases were stratified by race. Outcomes were compared between matched racial cohorts. Multivariate regression analyses were performed to determine whether race independently predicted morbidity.

RESULTS

From 2015 to 2018, 29,394 elderly NHW (90.8%) and NHB (9.2%) patients underwent an RYGB or SG. At baseline, NHB elderly patients had a higher burden of co-morbid conditions, resulting in higher rates of overall (7.7% versus 6.4%, P = .009) and bariatric-related (5.4% versus 4.1%, P = .001) morbidity. All outcome measures were similar between propensity-score-matched racial elderly bariatric patient cohorts. On regression analysis, NHB race remained independently correlated with morbidity (odds ratio [OR] 1.3, 95% CI 1.08-1.47, P = .003).

CONCLUSION

RYGB and SG are safe in elderly patient cohorts, with no differences in adverse outcomes between NHB and NHW patients, accounting for confounding factors. While race does not appear to impact outcomes in the elderly cohorts, NHB race may play a role in access.

摘要

背景

已有研究表明,老年患者行减重手术是安全的,但与非老年患者相比,其不良结局发生率更高。种族对减重手术结局的影响仍在探索之中,最近的研究表明,黑种人患者的不良结局发生率更高。关于老年减重患者种族队列的围手术期结局在很大程度上仍未得到探索。

目的

本研究旨在比较非西班牙裔黑种人(NHB)和非西班牙裔白种人(NHW)老年减重手术患者的结局,以确定种族是否对结局有影响。

设置

学术医院。

方法

从代谢和减重外科认证和质量改进计划参与者使用数据文件(MBSAQIP PUF)中确定了 2015 年至 2018 年期间行原发性 Roux-en-Y(RYGB)和袖状胃切除术(SG)且年龄至少 65 岁的患者。根据种族对选定病例进行分层。比较匹配的种族队列之间的结局。进行多变量回归分析,以确定种族是否独立预测发病率。

结果

2015 年至 2018 年,29394 例老年 NHW(90.8%)和 NHB(9.2%)患者行 RYGB 或 SG。基线时,NHB 老年患者合并症负担更高,导致总体发病率(7.7%对 6.4%,P=0.009)和与减重相关的发病率(5.4%对 4.1%,P=0.001)更高。在倾向评分匹配的种族老年减重患者队列中,所有结局测量均相似。回归分析显示,NHB 种族与发病率独立相关(比值比[OR] 1.3,95%CI 1.08-1.47,P=0.003)。

结论

RYGB 和 SG 应用于老年患者队列是安全的,NHB 和 NHW 患者的不良结局无差异,考虑到混杂因素。虽然种族似乎不会影响老年患者队列的结局,但 NHB 种族可能在治疗机会方面发挥作用。

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