Advanced GI and Bariatrics Division, Department of Surgery, Mayo Clinic, Jacksonville, FL, 32224, USA.
Department of Surgery, Mayo Clinic Alix School of Medicine, 4500 San Pablo Rd S, Jacksonville, FL, 32224, USA.
Obes Surg. 2023 May;33(5):1411-1421. doi: 10.1007/s11695-023-06541-2. Epub 2023 Mar 14.
Roux-en-Y gastric bypass (RYGB) continues to be safely performed in racial cohorts. However, studies continue to report differences in complications, with non-Hispanic black (NHB) patients having a higher rate of adverse outcomes, including mortality. It is unclear how these disparate outcomes have evolved over time. Our objective was to determine RYGB procedure and mortality trends in racial cohorts.
Using the 2015 to 2019 Metabolic and Bariatric Surgery Accreditation and Quality Improvement Project (MBSAQIP) database, we identified primary RYGB cases performed laparoscopically or robotically. Non-Hispanic white (NHW) and non-Hispanic black (NHB) patient cohorts were matched based on patient and surgical characteristics. Conditional logistic regression analysis was conducted on the matched pairs. Primary outcomes of interest included year-to-year all-cause and procedure-related mortality. Stata/MP 16.1 was utilized for analysis, and a p-value of < 0.05 and a 95% confidence interval that excluded 1 were considered significant.
A total of 148,829 RYGB cases in NHW (82.8%) and Black (17.2%) patients were analyzed. RYGB trends remain similar for NHB and NHW patients over 5 years. In matched cohorts, all-cause mortality (OR 2.23; 95% CI: 1.16-4.29), aggregate related readmission (OR 1.39; 95% CI: 1.27-1.51), related reintervention (OR 1.36; 95% CI: 1.19-1.56), and VTE (OR 1.86; 95% CI: 1.40-2.45) were more likely in NHB patients. During the study period, year-to-year mortality was higher in NHB patients compared to NHW patients.
Over a 5-year period, year-to-year mortality remains higher in NHB patients after RYGB. While bariatric outcomes continue to improve, outcome gaps between racial cohorts seem to persist.
Roux-en-Y 胃旁路术(RYGB)在不同种族人群中仍然安全进行。然而,研究继续报告并发症存在差异,非西班牙裔黑种人(NHB)患者的不良结局发生率更高,包括死亡率。目前尚不清楚这些不同的结果是如何随时间演变的。我们的目的是确定不同种族队列中 RYGB 手术和死亡率的趋势。
使用 2015 年至 2019 年代谢和减肥手术认证和质量改进项目(MBSAQIP)数据库,我们确定了腹腔镜或机器人辅助下进行的原发性 RYGB 手术。根据患者和手术特点,对非西班牙裔白种人(NHW)和非西班牙裔黑种人(NHB)患者队列进行匹配。对匹配对进行条件逻辑回归分析。主要观察指标包括逐年全因和与手术相关的死亡率。使用 Stata/MP 16.1 进行分析,p 值<0.05 且 95%置信区间不包括 1 被认为具有统计学意义。
共分析了 148829 例 NHW(82.8%)和黑人(17.2%)患者的 RYGB 手术。在 5 年的时间里,NHB 和 NHW 患者的 RYGB 趋势仍然相似。在匹配队列中,全因死亡率(OR 2.23;95%CI:1.16-4.29)、总相关再入院率(OR 1.39;95%CI:1.27-1.51)、相关再干预率(OR 1.36;95%CI:1.19-1.56)和 VTE(OR 1.86;95%CI:1.40-2.45)在 NHB 患者中更常见。在研究期间,与 NHW 患者相比,RYGB 后 NHB 患者的年死亡率更高。
在 5 年期间,RYGB 后 NHB 患者的年死亡率仍然较高。虽然减肥效果继续改善,但不同种族队列之间的结果差距似乎仍然存在。