[用于提取致动脉粥样硬化脂蛋白的亲和吸附剂的合成与性质]
[Synthesis and properties of an affinity sorbent for extraction of atherogenic lipoproteins].
作者信息
Andrianova I P, Rabovskiĭ A B, Zuevskiĭ V V, Tsybul'skaia M V, Samoĭlova N A
出版信息
Bioorg Khim. 1986 Oct;12(10):1391-5.
PMID:3468950
Abstract
A digitonin-containing affinity sorbent was prepared using a hydrophilic polymer carrier. The correlation was found between the polymer structure and crosslink. King degree, on the one hand, and the sorbent capacity to bind cholesterol, protein and lipoproteins--on the other. The sorbent was demonstrated to extract predominantly atherogenic lipoproteins from blood plasma.
摘要
使用亲水性聚合物载体制备了含洋地黄皂苷的亲和吸附剂。发现聚合物结构与交联度、金氏度之间存在相关性，另一方面，也发现了吸附剂结合胆固醇、蛋白质和脂蛋白的能力之间存在相关性。已证明该吸附剂主要从血浆中提取致动脉粥样硬化脂蛋白。
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