Nyholm D, Jost W H
Department of Neuroscience, Neurology, Uppsala University, Uppsala, Sweden.
Parkinson-Klinik Ortenau, Kreuzbergstr. 12, 77709, Wolfach, Germany.
Neurol Res Pract. 2021 Oct 25;3(1):58. doi: 10.1186/s42466-021-00157-6.
Calculation of levodopa-equivalent dose in Parkinson's disease has become common in research, but is also a useful tool in clinical practice, especially when initiating device-aided treatments (deep brain stimulation, apomorphine and levodopa infusions). The aim with the present calculator is to provide an updated conversion table, including dose calculation of the recently developed levodopa/entacapone/carbidopa intestinal gel infusion. Future versions of the calculator should be made conducive to learning by means of artificial intelligence.
帕金森病中左旋多巴等效剂量的计算在研究中已很常见,但在临床实践中也是一种有用的工具,尤其是在启动器械辅助治疗(深部脑刺激、阿扑吗啡和左旋多巴输注)时。本计算器的目的是提供一个更新的转换表,包括最近开发的左旋多巴/恩他卡朋/卡比多巴肠凝胶输注的剂量计算。该计算器的未来版本应借助人工智能便于学习。