Division of Transfusion Medicine, Department of Pathology, City of Hope National Medical Center, Duarte, CA 91010-3000, USA.
Division of Transfusion Medicine, Department of Pathology and Laboratory Medicine, Henry Ford Hospital, K6, 2799 West Grand Boulevard, Detroit, MI 48202, USA; Department of Pathology, Wayne State University School of Medicine, Detroit, MI, USA.
Clin Lab Med. 2021 Dec;41(4):621-634. doi: 10.1016/j.cll.2021.07.005. Epub 2021 Sep 30.
Platelets are commonly transfused either therapeutically or prophylactically to maintain hemostasis. Most platelet transfusions are used to manage patients with hematologic malignancies. Although platelet transfusion guidelines have been published, platelet transfusion practices are still heterogeneous. Platelet transfusion guidelines partly lack recommendations or differ in the platelet threshold recommendations in some clinical situations. This article reviews platelet transfusions focusing on transfusion guidelines and platelet thresholds in different clinical settings.
血小板通常被用于治疗或预防目的进行输注,以维持止血。大多数血小板输注用于治疗血液系统恶性肿瘤患者。尽管已经发布了血小板输注指南,但血小板输注实践仍然存在异质性。在某些临床情况下,血小板输注指南部分缺乏建议或在血小板阈值建议上存在差异。本文主要关注不同临床环境下的输注指南和血小板阈值,对血小板输注进行了综述。