van der Zee Ymie J, Stiers Peter L J, Lagae Lieven, Evenhuis Heleen M
Royal Dutch Visio, Rotterdam, Netherlands.
Department of General Practice, Intellectual Disability Medicine, Erasmus MC, Rotterdam, Netherlands.
Front Hum Neurosci. 2021 Oct 7;15:733054. doi: 10.3389/fnhum.2021.733054. eCollection 2021.
In this study, we examined (1) the presence of abnormally low scores (below 10 percentile) in various visual motion perception aspects in children with brain damage, while controlling for their cognitive developmental delay; (2) whether the risk is increased in comparison with the observation and expectation in a healthy control group and healthy population. Performance levels of 46 children with indications of brain damage (M = 7y4m, SD = 2y4m) on three visual motion perception aspects (global motion, motion speed, motion-defined form) were evaluated. We used developmental age as entry of a preliminary reference table to classify the patient's performance levels. Then we compared the percentages of abnormally low scores with percentages expected in the healthy population using estimated base rates and the observed percentages in the control sample ( = 119). When using developmental age as reference level, the percentage of low scores on at least one of the three tasks was significantly higher than expected in the healthy population [19/46, 41% (95%CI: 28-56%), = 0.03]. In 15/19 (79% [95%CI: 61-97%] patients only one aspect of motion perception was affected. Four patients performed abnormally low on two out of three tasks, which is also higher than expected (4/46, 8.7%, 95%CI: 2.4-20.8% vs. 2.1%; = 2.61, < 0.01). The observed percentages in the patient group were also higher than found in the control group. There is some evidence that children with early brain damage have an increased risk of isolated and combined motion perception problems, independent of their performance IQ.
在本研究中，我们考察了：（1）脑损伤儿童在各种视觉运动感知方面是否存在异常低分（低于第10百分位数），同时控制其认知发育迟缓情况；（2）与健康对照组和健康人群的观察结果及预期相比，风险是否增加。评估了46名有脑损伤迹象的儿童（平均年龄7岁4个月，标准差2岁4个月）在三个视觉运动感知方面（整体运动、运动速度、运动定义形状）的表现水平。我们使用发育年龄作为初步参考表的条目来对患者的表现水平进行分类。然后，我们使用估计的基础率和对照组样本（n = 119）中的观察百分比，将异常低分的百分比与健康人群中的预期百分比进行比较。当以发育年龄作为参考水平时，三项任务中至少一项得分低的百分比显著高于健康人群中的预期[19/46，41%（95%置信区间：28 - 56%），P = 0.03]。在15/19（79%[95%置信区间：61 - 97%]）名患者中，只有一个运动感知方面受到影响。4名患者在三项任务中的两项表现异常低，这也高于预期（4/46，8.7%，95%置信区间：2.4 - 20.8% vs. 2.1%；P = 2.61，P < 0.01）。患者组中的观察百分比也高于对照组中的观察百分比。有证据表明，早期脑损伤儿童存在孤立和综合运动感知问题的风险增加，与他们的操作智商无关。
