Mallise Carly A, Murphy Vanessa E, Campbell Linda E, Woolard Alix J, Whalen Olivia M, Milton Gabrielle, Mattes Joerg, Collison Adam, Gibson Peter G, Karayanidis Frini, Lane Alison E
School of Psychological Sciences, University of Newcastle, Callaghan, NSW, Australia.
Priority Research Centre GrowUpWell®, University of Newcastle, Callaghan, NSW, Australia.
Front Psychol. 2021 Oct 8;12:713804. doi: 10.3389/fpsyg.2021.713804. eCollection 2021.
Maternal asthma in pregnancy is associated with an increased risk of adverse perinatal outcomes. Adverse perinatal outcomes may result in poorer infant developmental outcomes, such as temperament and sensory difficulties. This study aimed to (1) assess differences in temperament and sensory features between infants born to mothers with and without asthma and (2) investigate differences in these infant behaviours as a function of maternal asthma severity and asthma control. Mothers completed the Carey Temperament Scales and the Sensory Profile 2 at either 6 weeks, 6 months, or 12 months postpartum. Overall, we observed no significant differences between infants born to mothers with and without asthma in their temperament or sensory features; scores in both domains fell within the normative range. More infants in the asthma group, however, were reported to be highly distractible. When compared with normative data, infants in both groups were reported to have poor predictability of biological functions and fewer infants engaged in low levels of sensory behaviours. Some infants were observed to experience difficulties with hyper-reactivity within several domains. Maternal asthma severity and control during pregnancy were not linked to significant differences between infant temperament and sensory features. The present findings indicate that infants born to mothers with asthma are not at an increased risk overall for temperament or sensory difficulties, compared to control infants. However, a subset of infants across both groups may be at risk for attention or sensory hyper-reactivity difficulties. Further research into the developmental outcomes of infants born to mothers with asthma is warranted.
孕期母亲哮喘与不良围产期结局风险增加相关。不良围产期结局可能导致婴儿发育结局较差，如气质和感觉方面的困难。本研究旨在：（1）评估患哮喘和未患哮喘母亲所生婴儿在气质和感觉特征方面的差异；（2）调查这些婴儿行为差异与母亲哮喘严重程度和哮喘控制情况的关系。母亲们在产后6周、6个月或12个月时完成了凯里气质量表和感觉概况2。总体而言，我们观察到患哮喘和未患哮喘母亲所生婴儿在气质或感觉特征方面无显著差异；两个领域的得分均在正常范围内。然而，据报告，哮喘组中有更多婴儿极易分心。与正常数据相比，两组婴儿的生理功能可预测性均较差，且参与低水平感觉行为的婴儿较少。观察到一些婴儿在多个领域存在反应过度的困难。孕期母亲哮喘的严重程度和控制情况与婴儿气质和感觉特征之间的显著差异无关。目前的研究结果表明，与对照婴儿相比，患哮喘母亲所生婴儿在气质或感觉方面出现困难的总体风险并未增加。然而，两组中的一部分婴儿可能存在注意力或感觉反应过度方面的困难。有必要对患哮喘母亲所生婴儿的发育结局进行进一步研究。
