• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

A cynomolgus monkey with naturally occurring Parkinson's disease.

作者信息

Li Hao, Su Ling-Yan, Yang Lixin, Li Min, Liu Qianjin, Li Zhenhui, Hu Yan, Li Hongwei, Wu Shihao, Wang Wenchao, Hu Yingzhou, Wang Zhengbo, Rizak Joshua D, Huang Baihui, Xu Min, Wu Jing, Lv Long-Bao, Turck Christoph W, Yin Yong, Yao Yong-Gang, Su Bing, Hu Xintian

机构信息

Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, China.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, China.

出版信息

Natl Sci Rev. 2020 Dec 10;8(3):nwaa292. doi: 10.1093/nsr/nwaa292. eCollection 2021 Mar.

DOI:10.1093/nsr/nwaa292
PMID:34691601
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8288342/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a3f/8288342/675cb8400ec0/nwaa292fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a3f/8288342/675cb8400ec0/nwaa292fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a3f/8288342/675cb8400ec0/nwaa292fig1.jpg

相似文献

1
A cynomolgus monkey with naturally occurring Parkinson's disease.一只患有自然发生帕金森病的食蟹猴。
Natl Sci Rev. 2020 Dec 10;8(3):nwaa292. doi: 10.1093/nsr/nwaa292. eCollection 2021 Mar.
2
Opicapone enhances the reversal of MPTP-induced Parkinson-like syndrome by levodopa in cynomolgus monkeys.奥匹卡朋增强左旋多巴对食蟹猴中 MPTP 诱导的帕金森样综合征的逆转作用。
Eur J Pharmacol. 2021 Feb 5;892:173742. doi: 10.1016/j.ejphar.2020.173742. Epub 2020 Nov 18.
3
Comparative plasma lipidome between human and cynomolgus monkey: are plasma polar lipids good biomarkers for diabetic monkeys?人与食蟹猴血浆脂质组比较:血浆极性脂质是否为糖尿病猴的良好生物标志物?
PLoS One. 2011 May 4;6(5):e19731. doi: 10.1371/journal.pone.0019731.
4
Electroporation of cynomolgus monkey embryonic stem cells.食蟹猴胚胎干细胞的电穿孔法
Genesis. 2003 Dec;37(4):180-7. doi: 10.1002/gene.10246.
5
Investigation of cynomolgus monkey complement.食蟹猴补体的研究
Transplant Proc. 2008 Mar;40(2):607-8. doi: 10.1016/j.transproceed.2008.01.008.
6
Studies of monkey complement: measurement of cynomolgus monkey CH50, ACH50, C4, C2 and C3.猕猴补体研究:食蟹猴CH50、ACH50、C4、C2和C3的测定
Xenotransplantation. 2008 Feb;15(1):14-9. doi: 10.1111/j.1399-3089.2007.00438.x.
7
Comparison of inducibility of multidrug resistance (MDR)1, multidrug resistance-associated protein (MRP)1, and MRP2 mRNAs by prototypical microsomal enzyme inducers in primary cultures of human and cynomolgus monkey hepatocytes.在原代培养的人肝细胞和食蟹猴肝细胞中,比较典型微粒体酶诱导剂对多药耐药性(MDR)1、多药耐药相关蛋白(MRP)1和MRP2 mRNA的诱导能力。
Biol Pharm Bull. 2008 Nov;31(11):2068-72. doi: 10.1248/bpb.31.2068.
8
Similar substrate specificity of cynomolgus monkey cytochrome P450 2C19 to reported human P450 2C counterpart enzymes by evaluation of 89 drug clearances.通过评估89种药物清除率,食蟹猴细胞色素P450 2C19与已报道的人类P450 2C对应酶具有相似的底物特异性。
Biopharm Drug Dispos. 2015 Dec;36(9):636-43. doi: 10.1002/bdd.1991.
9
Cynomolgus monkey induced pluripotent stem cells established by using exogenous genes derived from the same monkey species.利用源自同一猴种的外源基因建立的食蟹猴诱导多能干细胞。
Differentiation. 2013 Apr-Jun;85(4-5):131-9. doi: 10.1016/j.diff.2013.02.004. Epub 2013 Jun 19.
10
Newly identified CYP2C93 is a functional enzyme in rhesus monkey, but not in cynomolgus monkey.新鉴定的 CYP2C93 是恒河猴中的一种功能性酶,但不是食蟹猴中的功能性酶。
PLoS One. 2011 Feb 8;6(2):e16923. doi: 10.1371/journal.pone.0016923.

引用本文的文献

1
Pursuing innovation in a new era.在新时代追求创新。
Zool Res. 2024 Nov 18;45(6):1232-1234. doi: 10.24272/j.issn.2095-8137.2024.326.
2
Parkinson's Disease: Cells Succumbing to Lifelong Dopamine-Related Oxidative Stress and Other Bioenergetic Challenges.帕金森病:细胞长期遭受多巴胺相关氧化应激和其他生物能量挑战的影响。
Int J Mol Sci. 2024 Feb 7;25(4):2009. doi: 10.3390/ijms25042009.
3
Genetically modified non-human primate models for research on neurodegenerative diseases.用于神经退行性疾病研究的基因修饰非人灵长类动物模型。

本文引用的文献

1
Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes.路易体病理存在于帕金森病中,由挤在一起的细胞器和脂膜组成。
Nat Neurosci. 2019 Jul;22(7):1099-1109. doi: 10.1038/s41593-019-0423-2. Epub 2019 Jun 24.
2
Microglia in neurodegeneration.神经退行性疾病中的小胶质细胞。
Nat Neurosci. 2018 Oct;21(10):1359-1369. doi: 10.1038/s41593-018-0242-x. Epub 2018 Sep 26.
3
Neuropathology of Parkinson disease.帕金森病的神经病理学。
Zool Res. 2024 Mar 18;45(2):263-274. doi: 10.24272/j.issn.2095-8137.2023.197.
4
Editorial of non-human primate research.非人灵长类动物研究社论
Natl Sci Rev. 2023 Dec 21;10(11):nwad326. doi: 10.1093/nsr/nwad326. eCollection 2023 Nov.
5
Cath-KP, a novel peptide derived from frog skin, prevents oxidative stress damage in a Parkinson's disease model.Cath-KP,一种源自青蛙皮肤的新型肽,可预防帕金森病模型中的氧化应激损伤。
Zool Res. 2024 Jan 18;45(1):108-124. doi: 10.24272/j.issn.2095-8137.2023.101.
6
Circuit-specific gene therapy is knocking on the door of Parkinson's disease.针对特定神经回路的基因疗法正在叩响帕金森病治疗的大门。
Zool Res. 2023 Nov 18;44(6):1152-1153. doi: 10.24272/j.issn.2095-8137.2023.353.
7
The importance of social behavior in nonhuman primate studies of aging: A mini-review.社交行为在非人类灵长类动物衰老研究中的重要性:一篇综述。
Neurosci Biobehav Rev. 2023 Nov;154:105422. doi: 10.1016/j.neubiorev.2023.105422. Epub 2023 Oct 6.
8
Outlook of PINK1/Parkin signaling in molecular etiology of Parkinson's disease, with insights into knockout models.PINK1/Parkin 信号在帕金森病分子病因学中的展望,以及对敲除模型的深入了解。
Zool Res. 2023 May 18;44(3):559-576. doi: 10.24272/j.issn.2095-8137.2022.406.
9
Evolutionary and genomic perspectives of brain aging and neurodegenerative diseases.大脑衰老和神经退行性疾病的进化和基因组观点。
Prog Brain Res. 2023;275:165-215. doi: 10.1016/bs.pbr.2022.10.004. Epub 2023 Feb 3.
10
Functional genomics identify causal variant underlying the protective CTSH locus for Alzheimer's disease.功能基因组学鉴定出阿尔茨海默病保护性 CTSH 基因座的潜在因果变异。
Neuropsychopharmacology. 2023 Oct;48(11):1555-1566. doi: 10.1038/s41386-023-01542-2. Epub 2023 Feb 4.
Parkinsonism Relat Disord. 2018 Jan;46 Suppl 1(Suppl 1):S30-S33. doi: 10.1016/j.parkreldis.2017.07.033. Epub 2017 Aug 1.
4
Parkinson's disease.帕金森病。
Lancet. 2015 Aug 29;386(9996):896-912. doi: 10.1016/S0140-6736(14)61393-3. Epub 2015 Apr 19.
5
Cerebrospinal fluid biochemical studies in patients with Parkinson's disease: toward a potential search for biomarkers for this disease.帕金森病患者的脑脊液生化研究:寻找这种疾病潜在生物标志物的方法。
Front Cell Neurosci. 2014 Nov 11;8:369. doi: 10.3389/fncel.2014.00369. eCollection 2014.
6
Aging in rhesus monkeys: relevance to human health interventions.恒河猴衰老:与人类健康干预的相关性。
Science. 2004 Sep 3;305(5689):1423-6. doi: 10.1126/science.1102541.
7
alpha-Synuclein is phosphorylated in synucleinopathy lesions.α-突触核蛋白在突触核蛋白病损伤中发生磷酸化。
Nat Cell Biol. 2002 Feb;4(2):160-4. doi: 10.1038/ncb748.
8
Alpha-synuclein in Lewy bodies.路易小体中的α-突触核蛋白。
Nature. 1997 Aug 28;388(6645):839-40. doi: 10.1038/42166.
9
Developing a stable bilateral model of parkinsonism in rhesus monkeys.在恒河猴中建立稳定的帕金森病双侧模型。
Neuroscience. 1993 Jan;52(1):7-16. doi: 10.1016/0306-4522(93)90176-g.
10
Idiopathic Parkinson's disease and the Lewy body disorders.特发性帕金森病与路易体痴呆症
Neuropathol Appl Neurobiol. 1986 May-Jun;12(3):223-34. doi: 10.1111/j.1365-2990.1986.tb00136.x.