Mathematics of microRNAs: stabilizing gene regulatory networks.
作者信息
Ambros Victor
机构信息
Program in Molecular Medicine, University of Massachusetts Medical School, UK.
出版信息
Natl Sci Rev. 2019 Nov;6(6):1189-1190. doi: 10.1093/nsr/nwz112. Epub 2019 Aug 13.
Abstract
摘要
相似文献
1
Mathematics of microRNAs: stabilizing gene regulatory networks.微小RNA的数学原理：稳定基因调控网络
Natl Sci Rev. 2019 Nov;6(6):1189-1190. doi: 10.1093/nsr/nwz112. Epub 2019 Aug 13.
2
Stabilizing gene regulatory networks through feedforward loops.通过前馈回路稳定基因调控网络。
Chaos. 2013 Jun;23(2):025107. doi: 10.1063/1.4808248.
3
Genes under weaker stabilizing selection increase network evolvability and rapid regulatory adaptation to an environmental shift.处于较弱稳定选择下的基因会增加网络的进化能力以及对环境变化的快速调控适应能力。
J Evol Biol. 2016 Aug;29(8):1602-16. doi: 10.1111/jeb.12897. Epub 2016 Jun 20.
4
Intersection of MicroRNA and gene regulatory networks and their implication in cancer.微小RNA与基因调控网络的交叉及其在癌症中的意义。
Curr Pharm Biotechnol. 2014;15(5):445-54. doi: 10.2174/1389201015666140519120855.
5
The interplay between transcription factors and microRNAs in genome-scale regulatory networks.转录因子与微小RNA在全基因组规模调控网络中的相互作用。
Bioessays. 2009 Apr;31(4):435-45. doi: 10.1002/bies.200800212.
6
Synergistic regulatory networks mediated by microRNAs and transcription factors under drought, heat and salt stresses in Oryza Sativa spp.水稻在干旱、高温和盐胁迫下由微小RNA和转录因子介导的协同调控网络
Gene. 2015 Jan 25;555(2):127-39. doi: 10.1016/j.gene.2014.10.054. Epub 2014 Oct 31.
7
Quantifying gene networks with regulatory strengths.通过调控强度对基因网络进行量化。
Mol Biol Rep. 2002;29(1-2):73-7. doi: 10.1023/a:1020310504986.
8
Inferring the perturbed microRNA regulatory networks in cancer using hierarchical gene co-expression signatures.利用分层基因共表达特征推断癌症中受干扰的微小RNA调控网络。
PLoS One. 2013 Nov 20;8(11):e81032. doi: 10.1371/journal.pone.0081032. eCollection 2013.
9
Modelling and analysis of gene regulatory networks.基因调控网络的建模与分析
Nat Rev Mol Cell Biol. 2008 Oct;9(10):770-80. doi: 10.1038/nrm2503. Epub 2008 Sep 17.
10
miRNA-target gene regulatory networks: A Bayesian integrative approach to biomarker selection with application to kidney cancer.微小RNA-靶基因调控网络：一种用于生物标志物选择的贝叶斯整合方法及其在肾癌中的应用
Biometrics. 2015 Jun;71(2):428-38. doi: 10.1111/biom.12266. Epub 2015 Jan 30.
引用本文的文献
1
Nuclear localization of Argonaute 2 is affected by cell density and may relieve repression by microRNAs.Argonaute 2 的核定位受细胞密度的影响，并且可能通过 microRNAs 缓解抑制。
Nucleic Acids Res. 2024 Feb 28;52(4):1930-1952. doi: 10.1093/nar/gkad1155.
2
Nuclear Localization of Argonaute is affected by Cell Density and May Relieve Repression by microRNAs.AGO蛋白的核定位受细胞密度影响，且可能解除miRNA的抑制作用。
bioRxiv. 2023 Jul 12:2023.07.07.548119. doi: 10.1101/2023.07.07.548119.
3
Consequences of depleting TNRC6, AGO, and DROSHA proteins on expression of microRNAs.耗尽 TNRC6、AGO 和 DROSHA 蛋白对 microRNAs 表达的影响。
RNA. 2023 Aug;29(8):1166-1184. doi: 10.1261/rna.079647.123. Epub 2023 May 11.
4
Canalization of Phenotypes-When the Transcriptome is Constantly but Weakly Perturbed.表型 canalization- 当转录组持续但微弱地受到干扰时。
Mol Biol Evol. 2023 Jan 4;40(1). doi: 10.1093/molbev/msad005.
本文引用的文献
1
Gene regulatory network stabilized by pervasive weak repressions: microRNA functions revealed by the May-Wigner theory.由普遍存在的微弱抑制作用稳定的基因调控网络：May-Wigner理论揭示的微小RNA功能
Natl Sci Rev. 2019 Nov;6(6):1176-1188. doi: 10.1093/nsr/nwz076. Epub 2019 Jul 25.
2
Robust Distal Tip Cell Pathfinding in the Face of Temperature Stress Is Ensured by Two Conserved microRNAS in Caenorhabditis elegans.秀丽隐杆线虫中两个保守的 microRNA 确保了面对温度应激时强大的远端末梢细胞路径寻找。
Genetics. 2015 Aug;200(4):1201-18. doi: 10.1534/genetics.115.179184. Epub 2015 Jun 15.
3
Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress.秀丽隐杆线虫let-7家族的微小RNA在先天免疫反应通路中发挥作用，并赋予针对病原体应激的稳健发育时序。
Proc Natl Acad Sci U S A. 2015 May 5;112(18):E2366-75. doi: 10.1073/pnas.1422858112. Epub 2015 Apr 20.
4
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues.mRNA 不稳定性是哺乳动物 microRNAs 的主要作用，此时会出现实质性的抑制。
Mol Cell. 2014 Oct 2;56(1):104-15. doi: 10.1016/j.molcel.2014.08.028. Epub 2014 Sep 25.
5
Contributions of mRNA abundance, ribosome loading, and post- or peri-translational effects to temporal repression of C. elegans heterochronic miRNA targets.mRNA 丰度、核糖体加载以及翻译后或翻译周边效应对 C. elegans 时序性 miRNA 靶标抑制的贡献。
Genome Res. 2012 Dec;22(12):2418-26. doi: 10.1101/gr.136515.111. Epub 2012 Aug 1.
6
Roles for microRNAs in conferring robustness to biological processes.miRNAs 在赋予生物过程稳健性方面的作用。
Cell. 2012 Apr 27;149(3):515-24. doi: 10.1016/j.cell.2012.04.005.
7
Ribosome profiling shows that miR-430 reduces translation before causing mRNA decay in zebrafish.核糖体图谱分析表明，miR-430 在导致 zebrafish 中 mRNA 降解之前降低了翻译。
Science. 2012 Apr 13;336(6078):233-7. doi: 10.1126/science.1215704. Epub 2012 Mar 15.
8
Many families of C. elegans microRNAs are not essential for development or viability.许多秀丽隐杆线虫 microRNAs 家族对于发育和生存并非必需。
Curr Biol. 2010 Feb 23;20(4):367-73. doi: 10.1016/j.cub.2009.12.051. Epub 2010 Jan 21.
9
A microRNA imparts robustness against environmental fluctuation during development.一种微小RNA在发育过程中赋予对环境波动的稳健性。
Cell. 2009 Apr 17;137(2):273-82. doi: 10.1016/j.cell.2009.01.058.
10
Most Caenorhabditis elegans microRNAs are individually not essential for development or viability.大多数秀丽隐杆线虫的微小RNA对发育或生存能力并非不可或缺。
PLoS Genet. 2007 Dec;3(12):e215. doi: 10.1371/journal.pgen.0030215.
Zotero 插件