• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

吲哚美辛诱发的高血压危象

Indomethacin-Induced Hypertensive Crisis.

作者信息

Dhungana Bibek, Kansakar Sajog, Paudel Palak, Kc Bibek, Guragain Ashish

机构信息

Internal Medicine, KIST Medical College, Lalitpur, NPL.

Internal Medicine, Manipal College of Medical Sciences, Pokhara, NPL.

出版信息

Cureus. 2021 Sep 17;13(9):e18043. doi: 10.7759/cureus.18043. eCollection 2021 Sep.

DOI:10.7759/cureus.18043
PMID:34692276
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8525672/
Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly prescribed drugs to treat pain, and are easily available over the counter in lower dosages. NSAID use is associated with various side effects and elevated blood pressure is one of them. NSAIDs vary considerably in their effect on blood pressure with indomethacin being one of the NSAIDs associated with a significant increase in blood pressure. We present a case of a 58-year-old woman who developed a hypertensive crisis after a single dose of prescription indomethacin.

摘要

非甾体抗炎药(NSAIDs)是治疗疼痛最常用的处方药之一,较低剂量的此类药物在柜台即可轻易买到。使用NSAIDs会引发各种副作用,血压升高就是其中之一。不同NSAIDs对血压的影响差异很大,吲哚美辛是会导致血压显著升高的NSAIDs之一。我们报告一例58岁女性患者,其在单次服用处方剂量的吲哚美辛后发生高血压危象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a37e/8525672/66bb32827635/cureus-0013-00000018043-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a37e/8525672/66bb32827635/cureus-0013-00000018043-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a37e/8525672/66bb32827635/cureus-0013-00000018043-i01.jpg

相似文献

1
Indomethacin-Induced Hypertensive Crisis.吲哚美辛诱发的高血压危象
Cureus. 2021 Sep 17;13(9):e18043. doi: 10.7759/cureus.18043. eCollection 2021 Sep.
2
A meta-analysis of the effects of nonsteroidal anti-inflammatory drugs on blood pressure.非甾体抗炎药对血压影响的荟萃分析。
Arch Intern Med. 1993 Feb 22;153(4):477-84.
3
NSAIDs and blood pressure. Clinical importance for older patients.非甾体抗炎药与血压。对老年患者的临床重要性。
Drugs Aging. 1998 Jan;12(1):17-27. doi: 10.2165/00002512-199812010-00003.
4
Prescription of nonsteroidal anti-inflammatory drugs for elderly people in Alberta.阿尔伯塔省老年人非甾体抗炎药的处方情况。
CMAJ. 1994 Aug 1;151(3):315-22.
5
The response to arachidonic acid before and after non-steroidal anti-inflammatory drugs in normotensive and hypertensive rats.
J Hypertens. 1994 Aug;12(8):891-9.
6
Comparative effects of non-steroidal anti-inflammatory drugs (NSAIDs) on blood pressure in patients with hypertension.非甾体抗炎药(NSAIDs)对高血压患者血压的比较影响。
BMC Cardiovasc Disord. 2012 Oct 24;12:93. doi: 10.1186/1471-2261-12-93.
7
Influence of non-steroidal anti-inflammatory drugs on renal function and 24h ambulatory blood pressure-reducing effects of enalapril and nifedipine gastrointestinal therapeutic system in hypertensive patients.
J Hypertens. 1995 Aug;13(8):925-31. doi: 10.1097/00004872-199508000-00014.
8
NSAIDs and increased blood pressure. What is the clinical significance?非甾体抗炎药与血压升高。其临床意义是什么?
Drug Saf. 1997 Nov;17(5):277-89. doi: 10.2165/00002018-199717050-00001.
9
The effects of sulindac and indomethacin on the anti-hypertensive and diuretic action of hydrochlorothiazide in patients with mild to moderate essential hypertension.舒林酸和吲哚美辛对轻度至中度原发性高血压患者氢氯噻嗪的降压和利尿作用的影响。
Br J Clin Pharmacol. 1986 Apr;21(4):417-23. doi: 10.1111/j.1365-2125.1986.tb05216.x.
10
NSAID-antihypertensive drug interactions: which outpatients are at risk for a rise in systolic blood pressure?非甾体抗炎药-抗高血压药物相互作用:哪些门诊患者有发生收缩压升高的风险?
Eur J Prev Cardiol. 2015 Jan;22(1):91-9. doi: 10.1177/2047487313505243. Epub 2013 Sep 16.

本文引用的文献

1
Non-steroidal anti-inflammatory drugs (NSAIDs) and organ damage: A current perspective.非甾体抗炎药(NSAIDs)与器官损伤:当前观点。
Biochem Pharmacol. 2020 Oct;180:114147. doi: 10.1016/j.bcp.2020.114147. Epub 2020 Jul 10.
2
Assessment of nonsteroidal anti-inflammatory drug use pattern using World Health Organization indicators: A cross-sectional study in a tertiary care teaching hospital of Chhattisgarh.使用世界卫生组织指标评估非甾体抗炎药使用模式:恰蒂斯加尔邦一家三级护理教学医院的横断面研究
Indian J Pharmacol. 2017 Nov-Dec;49(6):445-450. doi: 10.4103/ijp.IJP_189_17.
3
Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel Disease.
非甾体抗炎药与炎症性肠病
Pharmaceuticals (Basel). 2010 Apr 12;3(4):1084-1092. doi: 10.3390/ph3041084.
4
Trends in the use of aspirin and nonsteroidal anti-inflammatory drugs in the general U.S. population.美国普通人群中阿司匹林和非甾体抗炎药的使用趋势。
Pharmacoepidemiol Drug Saf. 2014 Jan;23(1):43-50. doi: 10.1002/pds.3463. Epub 2013 May 30.
5
Nonsteroidal anti-inflammatory drugs: adverse effects and their prevention.非甾体抗炎药:不良反应及其预防。
Semin Arthritis Rheum. 2010 Feb;39(4):294-312. doi: 10.1016/j.semarthrit.2008.08.001. Epub 2008 Sep 27.
6
Characteristics of meningitis caused by Ibuprofen: report of 2 cases with recurrent episodes and review of the literature.布洛芬所致脑膜炎的特征:2例复发病例报告及文献复习
Medicine (Baltimore). 2006 Jul;85(4):214-220. doi: 10.1097/01.md.0000229757.78057.50.
7
Treating osteoarthritis with cyclooxygenase-2-specific inhibitors: what are the benefits of avoiding blood pressure destabilization?使用环氧化酶-2特异性抑制剂治疗骨关节炎:避免血压不稳定有哪些益处?
Hypertension. 2005 Jan;45(1):92-7. doi: 10.1161/01.HYP.0000149684.01903.b8. Epub 2004 Nov 15.
8
The impact of nonsteroidal anti-inflammatory drugs on blood pressure, with an emphasis on newer agents.非甾体抗炎药对血压的影响,重点关注新型药物。
Clin Ther. 2003 Jan;25(1):1-18. doi: 10.1016/s0149-2918(03)90003-8.
9
The effect of nonsteroidal anti-inflammatory drugs on blood pressure in patients treated with different antihypertensive drugs.非甾体抗炎药对接受不同抗高血压药物治疗患者血压的影响。
J Clin Hypertens (Greenwich). 2003 Jan-Feb;5(1):53-7. doi: 10.1111/j.1524-6175.2003.00514.x.
10
Roles of cyclooxygenase (COX)-1 and COX-2 in prostanoid production by human endothelial cells: selective up-regulation of prostacyclin synthesis by COX-2.环氧化酶(COX)-1和COX-2在人内皮细胞前列腺素生成中的作用:COX-2对前列环素合成的选择性上调。
J Immunol. 2001 Sep 1;167(5):2831-8. doi: 10.4049/jimmunol.167.5.2831.