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1型单纯疱疹病毒脑炎病程迁延,治疗后脑脊液聚合酶链反应持续呈阳性

A Protracted Course of Herpes Simplex Virus Type 1 Encephalitis With Persistent Cerebrospinal Fluid Polymerase Chain Reaction Positivity Post Treatment.

作者信息

Abbott Andrew, Lusby Heather, Islam Shehla P

机构信息

Department of Infectious Diseases and Global Medicine, University of Florida College of Medicine, Gainesville, USA.

出版信息

Cureus. 2021 Sep 19;13(9):e18107. doi: 10.7759/cureus.18107. eCollection 2021 Sep.

Abstract

Herpes simplex virus type 1 encephalitis presenting as an undulating course for more than two weeks prior to treatment. Despite 21 days of intravenous acyclovir, the virus remained detectable in the cerebrospinal fluid. The patient was treated with an additional 21 days of acyclovir with further improvement in mental status.

摘要

单纯疱疹病毒1型脑炎在治疗前呈现出超过两周的波动病程。尽管静脉注射阿昔洛韦21天,但脑脊液中仍可检测到该病毒。患者又接受了21天的阿昔洛韦治疗,精神状态进一步改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/142b/8525692/5902b08f65a8/cureus-0013-00000018107-i01.jpg

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