Department of Nephrology, Monash Health, Clayton, Victoria, Australia.
Department of Medicine, Centre for Inflammatory Diseases, Monash University, Clayton, Victoria, Australia.
Transpl Infect Dis. 2022 Feb;24(1):e13749. doi: 10.1111/tid.13749. Epub 2021 Nov 3.
To identify barriers and enablers to COVID-19 vaccination in renal transplant recipients who are undecided about vaccination.
An online survey was distributed to 876 adult kidney transplant recipients at a tertiary referral service, who had not been vaccinated against COVID-19. The survey assessed willingness to be vaccinated, attitudes toward COVID-19 vaccines, and barriers and enablers to proceeding with vaccination.
The survey response rate was 54% (473/876). Three hundred and forty-six (73.1%) participants planned to receive vaccination (yes group), 105 (22.2%) were undecided, and 22 (4.7%) refused vaccination. The undecided group were younger but were not different in other demographic characteristics to the yes group. The undecided group were less positive toward (34.29% vs. 91.3%, p < .001) and more concerned about (93.3% vs. 25.1%, p < .001) vaccination than the yes group. Their concerns related to vaccine safety (including harm to their transplant), poor efficacy, and a lack of rigorous testing in transplant recipients. Undecided recipients had received less vaccine-specific information from medical specialists than the yes group. Most undecided participants (95.1%) were willing to proceed with vaccination with appropriate supports. The most desired supports were information and a recommendation to proceed with vaccination from their treating transplant specialist and team.
CONCLUSION(S): Concerns about vaccine safety (including harm to transplant), poor vaccine efficacy, and lack of rigorous testing were barriers to vaccine uptake. Most undecided recipients would proceed with vaccination with specific recommendations and vaccine information provided by their transplant specialist/team. These simple interventions can be readily implemented to optimize vaccine uptake.
确定对 COVID-19 疫苗犹豫不决的肾移植受者接种疫苗的障碍和促进因素。
向一家三级转诊服务机构的 876 名未接种 COVID-19 疫苗的成年肾移植受者分发了在线调查。该调查评估了接种疫苗的意愿、对 COVID-19 疫苗的态度以及接种疫苗的障碍和促进因素。
调查回复率为 54%（473/876）。346 名（73.1%）参与者计划接种疫苗（是组），105 名（22.2%）犹豫不决，22 名（4.7%）拒绝接种。犹豫不决的组更年轻，但在其他人口统计学特征上与是组没有差异。犹豫不决的组对疫苗接种的积极性较低（34.29%比 91.3%，p<.001），更担心（93.3%比 25.1%，p<.001）。他们对疫苗安全性（包括对移植的损害）、低疗效和在移植受者中缺乏严格测试的担忧。犹豫不决的受者从医学专家那里获得的疫苗特异性信息少于是组。大多数犹豫不决的参与者（95.1%）愿意在适当的支持下继续接种疫苗。最需要的支持是来自治疗移植专家和团队的信息和建议接种疫苗。
对疫苗安全性（包括对移植的损害）、低疗效和缺乏严格测试的担忧是疫苗接种的障碍。大多数犹豫不决的受者将在移植专家/团队提供的具体建议和疫苗信息的支持下继续接种疫苗。这些简单的干预措施可以很容易地实施，以优化疫苗接种率。
