Department of Pharmacy, Zhongshan Hospital, Fudan University, Shanghai, China.
Department of Oncology, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hum Vaccin Immunother. 2021 Dec 2;17(12):4999-5006. doi: 10.1080/21645515.2021.1984133. Epub 2021 Sep 29.
The mortality rate from COVID-19 appears to be higher in solid organ transplant (SOT) recipients when compared with other populations. Vaccination is a key strategy to prevent the COVID-19 pandemic. However, it is unclear how readily SOT recipients will get vaccinated against COVID-19. We conducted an internet-based survey to investigate the vaccination willingness among Chinese SOT recipients and further explore possible influencing factors. Eight hundred and thirteen respondents participated in the survey. Overall, 46 (5.7%) recipients were vaccinated against COVID-19, while 767 (94.3%) were not. Among those not vaccinated, 175 (22.8%) intended to be vaccinated, while 592 (77.2%) were categorized as vaccine-hesitant. The most common reason for vaccination hesitancy is fear of preexisting comorbidities, followed by fear of side effects and doctors' negative advice. Factors associated with vaccination willingness were as follows: with liver transplantation, the main source of information on COVID-19 vaccines was from medical doctors, scientists, and scientific journals, with at least college-level education, positive intention toward influenza vaccination during the current season, perceived importance of vaccination for SOT recipients, and having been vaccinated against influenza during the last season. Our survey indicated the necessity for SOT recipients to receive more comprehensive and accessible health education about vaccination and emphasized the critical role of transplantation physicians in promoting vaccine acceptance among SOT recipients. We hope that our survey results will help governments to better target communication in the ongoing COVID-19 vaccination campaign.
COVID-19 导致的死亡率在实体器官移植（SOT）受者中似乎高于其他人群。接种疫苗是预防 COVID-19 大流行的关键策略。然而，尚不清楚 SOT 受者接种 COVID-19 疫苗的意愿如何。我们进行了一项基于互联网的调查，以了解中国 SOT 受者的疫苗接种意愿，并进一步探讨可能的影响因素。813 名受访者参加了这项调查。总体而言，46 名（5.7%）受者接种了 COVID-19 疫苗，而 767 名（94.3%）未接种。在未接种疫苗的人群中，175 人（22.8%）打算接种疫苗，而 592 人（77.2%）被归类为疫苗犹豫者。疫苗犹豫的最常见原因是担心现有合并症，其次是担心副作用和医生的负面建议。与疫苗接种意愿相关的因素如下：肝移植患者，COVID-19 疫苗的主要信息来源是医生、科学家和科学期刊，至少接受过大学教育，对当前季节流感疫苗接种有积极意向，认为疫苗接种对 SOT 受者很重要，并且在上个季节接种过流感疫苗。我们的调查表明，SOT 受者需要接受更全面和更容易获得的疫苗接种健康教育，并强调移植医生在促进 SOT 受者接受疫苗方面的关键作用。我们希望我们的调查结果将有助于政府在正在进行的 COVID-19 疫苗接种运动中更好地进行针对性沟通。
