Department of Chemistry, Shahrekord University, Shahrekord, Iran.
Department of Chemistry, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran.
IET Nanobiotechnol. 2021 Apr;15(2):197-211. doi: 10.1049/nbt2.12006. Epub 2021 Feb 22.
In this work, Co-Sn-Cu oxides/graphene nanocomposite, 30-40 ± 0.5 nm in size, was synthesized by solid-state microwave irradiation. This method presents several advantages such as operational simplicity, fast, low cost, safe and energy efficient, and suitability for production of high purity of nanoparticles. Other advantages of this method are there is no need for the use of solvent, fuel, and surfactant. Co-Sn-Cu oxides/graphene nanocomposites have been characterized by Fourier transform infrared spectroscopy, X-ray diffraction, field emission scanning electron microscopy, transmission electron microscopy, vibrating sample magnetometer, energy-dispersive X-ray spectroscopy, and UV-Vis spectroscopy. The synthesized nanocomposites were used as novel highly efficient catalysts for the synthesis of 1,8-dioxo-octahydroxanthenes at room temperature. The catalysts are recoverable and can be reused for six runs without loss of their activity. Also, the obtained nanocomposites exhibited significant anticancer activity against breast cancer cells and they could induce apoptosis in cancer cells.
在这项工作中，Co-Sn-Cu 氧化物/石墨烯纳米复合材料通过固态微波辐照合成，尺寸为 30-40 ± 0.5nm。该方法具有操作简单、快速、低成本、安全和节能等优点，适合生产高纯度纳米粒子。该方法的其他优点是不需要使用溶剂、燃料和表面活性剂。Co-Sn-Cu 氧化物/石墨烯纳米复合材料通过傅里叶变换红外光谱、X 射线衍射、场发射扫描电子显微镜、透射电子显微镜、振动样品磁强计、能谱和紫外可见光谱进行了表征。所合成的纳米复合材料被用作新型高效催化剂，在室温下合成 1,8-二氧代-辛二氢氧杂蒽。催化剂可回收，可重复使用六次而不损失其活性。此外，所得到的纳米复合材料对乳腺癌细胞表现出显著的抗癌活性，并且能够诱导癌细胞凋亡。
